| | | Studies at Queensland Institute of Medical Research: | | No antigenic relationship was detected by complement-fixation or neutraliza- tion tests between MRM10434 antigen or antiserum and the following arboviruses or suspected arboviruses isolated or available in Australia: Group A (Sindbis, Ross River, Getah, Bebaru); Group B (Murray Valley encephalitis, Kunjin, Kokobera, Edge Hill, Stratford, Alfuy, JBE, SLE, dengue types 1-4); Koongol group (Koongol, Wongal); Mapputta group (Mapputta, Trubanaman, MK7532); Quaranfil group (Abal); Simbu group (Akabane, Samford); Corriparta group (Corriparta); Eubenangee group (Eubenangee); others (Kowanyama, Almpiwar, Upolu, ephemeral fever, Belmont, Wallal, Charleville, Wongorr, Ngaingan and MRM 14556). Relationship to Warrego virus (Ch9935 strain); first observed by the International Reference Centre, was confirmed: | | | | | MRM10434 Antigen | | MRM10434 Immune Serum |
|---|
| | CF | NT | | CF | NT |
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| Immune Serum, Antigen | Ht/Ho | Ratio | Ht/Ho | | Ht/Ho | Ratio | Ht/Ho |
|---|
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| | Warrego | 8/>128 | 1/>16 | 1.3/3.2 | | <8/64 | <1/8 | 0.5/1.5 |
| | Studies at International Reference Centre, Yale Arbovirus Unit: | | Comparison by complement-fixation test with 24 solvent-resistant arboviruses [3] showed two Australian strains Ch9935 and MRM10434 were related to each other but distinct from others tested. | | Mitchell River virus was not closely related to other members of the Warrego serogroup by blot hybridization; it should be placed in the ungrouped set of orbiviruses [5] . | | |
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