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  Mosqueiro   MQOV

Possible Arbovirus

No

3

Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.
Other Information
 

Lart Park
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
The antigen of Mosqueiro virus did not react in CF tests with the following grouping ascitic fluids distributed by the National Institutes of Health: groups A, B, C, Guama, Bunyamwera, Capim, Simbu, VSV, Phlebotomus, Tacaribe, California, Sakhalin, and Kemerovo; or with polyvalents Quaranfil, Patois, rabies, etc. (rabies, LCM, NDV, Herpes simplex, vaccinia), Palyam, Congo, Anopheles A, etc. (groups Anopheles A, Anopheles B, and Turlock), 1, 2, 3, 4, 5, 6, 8, 9, 10, and 12. It was also negative with Evandro Chagas Institute stock hyperimmune ascitic fluids or sera to the following viruses: Tacaiuma, Turlock Utinga, Tembe, GD VII, Mirim, Acara, Oropouche, Irituia, Timbo, Chaco, Marco, Lukuni, Pacui, Jurona, Agua Preta, rabies, Ieri, Melao, Araguari, Serra do Navio, Boracea, Cotia, Gamboa, Belem, BeAn 157575, Piry, Cocal, Bertioga, Kwatta, Amapari, Herpes simplex, EMC, Nariva, Moriche, Cayenne 241, Cayenne 404, Cayenne 564, Navarro, SPAn 2220, Bat salivary gland, MRM 1, and MRM 2, Inhangapi, Santarem, BeAn 228950, and mouse hepatitis. It showed a slight reaction with polyvalents 7 and Bwamba, and with ascitic fluids to Hart Park and Kamese viruses, which are included in these two pools respectively. The results below show the relationships between Mosqueiro, Hart Park, and Kamese viruses by the CF test. They also show that Mosqueiro virus is very closely related, if not identical, to CoAr 1279, a Colombian isolate:
 
Sera
Antigens Mosqueiro Hart Park Kamese CoAr 1279 Control


* Antibody titer/antigen titer; 0 = <4
Blank = not done
Mosqueiro > 128/40 * 8/4 4/4 2/40 0
Hart Park 0 > 256/40 0 0
Kamese 0 > 128/> 256 0
CoAr 1279 >128/40 8/4 4/4 2/40 0
Control 0 0 0 0 0
 
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