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  Nairobi sheep disease   NSDV

Arbovirus

No


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Nairobi Sheep Disease
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
Tested by NT and CF against the agents listed below with no evidence of antigenic relationship (cross tests done in all cases): chikungunya, Semliki Forest, Sindbis, dengue 1, dengue 2, Zika, Uganda S, West Nile, yellow fever, Wesselsbron, Spondweni, Kyasanur forest disease, Oriboca, Apeu, Bunyamwera, Simbu, Pongola, Bwamba fever, Rift Valley fever, Lunyo, encephalomyocarditis (Mengo).
In all instances in which an haemagglutinating antigen was available, NSD antiserum was tested against it but in no case has any relationship been found.
An hyperimmune antiserum to lymphocytic choriomeningitis failed to react with NSD by either NT or CF.
A low-titered relationship by CF, IFA and indirect HA demonstrated between CON and NSD viruses [9] , [10] . SIRACA has decided that these relations are no greater than those used to establish BUN Supergroup. The CON and NSD antigenic groups should be kept as two distinct serogroups.
Following these observations, intergroup antigenic relationships were demonstrated for viruses of the following serogroups: CHF-CON, NSD, DGK, QYB, HUG, and SAK(11). Genus status (Nairovirus genus) within the family Bunyaviridae then was assigned to this group of viruses [11] , [12] ;.
 


Editor's Note: It has recently been found that a close relationship exists between Nairobi sheep disease and Ganjam viruses as demonstrated by the CF test. Further studies are in progress to clarify this serological relationship (F.G. Davies and J. Casals, Personal communication).
 
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