| |
| An antigen prepared by acetone-ether extraction from suckling mouse brain infected with Nepuyo virus failed to react in CF with the following antisera: |
| |
|
| | EEE | Makonde | SF Naples | | WEE | Ntaya | Tacaiuma | | Semliki | Oriboca | Quaranfil (EgAr 1095) | | Chikungunya | Marituba | Chenuda (EgAr 1152) | | Sindbis | Apeu | Anopheles A | | Ilheus | Catu | Turlock | | Yellow fever | Guama | Bwamba | | St. louis | Bimiti | Rift Valley fever | | Dengue | California enc. | Simbu | | Rio Bravo | Melao | Mengo | | JBE | Bunyamwera | Lukuni | | West Nile | Wyeomyia | Triniti | | RSSE | Kairi | Ieri | | Spondweni | Cache Valley | Aruac | | Zika | Guaroa | Tacaribe | | | | GD VII |
|
| Hyperimmune mouse serum to Nepuyo virus inhibited hemagglutination by TRVL 34053-1 virus, a Group C virus which is closely related to Caraparu virus. |
| HI tests carried out by Dr. Robert Shope, Belem, and by Dr. Loring Whitman, New York, confirmed that Nepuyo is a Group C virus. Both found the virus to be closely related to a Belem Group C isolate, BeAn 10709 [4] . |
| Nepuyo is most closely related to Murutucu and Marituba by HI and NT, and to Apeu and Marituba by CF [4] . |
| SIRACA considers Nepuyo virus to be a distinct virus in the Marituba complex, one of four complexes comprising serogroup C. An unregistered virus, 63UII, was antigenically classified as a variety of Nepuyo virus [13] . |
| |
