| | | | | Experimental host and age | Passage history and strain | Inoculation Route-Dose | Evidence of infection | AST (days) | Titer log10/ml | |
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| | Several brain passages from mice with runting and/or alopecia on days 5-7 are required before the virus becomes fully mouse-adapted. | | | | Mice (nb) | P-6 | ic 0.01 | Death (1) | 3-4 | 8.5 | | | Mice (nb) | P-7 | ip 0.02 | Scattered deaths | | | | | Mice (nb) | | sc | | | | | | Mice (wn) | P-6 | ic 0.03 | Antibody | | | | | Mice (wn) | P-6 | ip 0.03 | Antibody | | | | | Mice (nb) | P-<6 | ic,ip,ic 0.03 | Alopecia, paralysis, sickness, runting, occasional death, antibody prod. (1,6) | | | | | hamster (yg) | P-9 | ip 0.1 | Antibody | | | | | chicks (wet) | P-10 | | Viremia | | | |
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