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Abbreviations
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Virus Name: Oropouche

Abbreviation: OROV

Status
Probable Arbovirus

Select Agent
No

SALS Level
3

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information
DOC Permit Required, Hepa Filtration

Antigenic Group
Simbu

Section IX - Experimental Arthropod Infection and Transmission

Arthropod species & virus source(a)	Method of Infection log10/ml (b)		Incubation period (c)		Transmision by bite (d)		Assay of arthropod, log10/ml (e)
	Feeding	Injected	Days	°C	Host	Ratio	Whole	Organ	System


ORO virus transmitted from viremic man to hamsters by bite of C. paranensis. Threshold dose was approximately 5.3 dex LD50/ml blood. Transmission 6-12 days after C. paranensis took blood meal (9).
Aedes aegypti and Anopheles quadrimaculatus: Virus passaged five times through salivary glands(7).
Culicoides paranensis were capable of biol. transmission of the virus 4-9 days post-feeding on viremia hamsters. No evidence of mechanical transmission of ORO virus by C. paranensis was obtained (8).
Aedes scapularis, Ae serratus, Culex quinquefasciatus and Psorophora ferox: multiplication of virus demonstrated after parenteral inoculation (1).

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