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  Ponteves   PTVV

Possible Arbovirus

No

3

Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.
Other Information
 

Uukuniemi
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
HI test:
Mouse hyperimmune serum for Ponteves tested against 8 units of each of the following antigens: Sindbis, chikungunya, yellow fever, West Nile, SLE, Ntaya, MVE, dengues 1 and 2, CEE, Bunyamwera, Tahyna, Sicilian SF, Naples SF. The serum diluted 1:10 failed to inhibit HA.
CF test:
The following hyperimmune sera or ascitic fluids were tested against Ponteves antigen (homologous titer with mouse serum 128/32*): Group A, Group B, Group Bunyamwera, Group Sandfly fevers, West Nile, Tahyna, Grand Arbaud, Uukuniemi [2] .
An immune serum against Potepli virus, a strain of Uukuniemi virus [3] , was also included in the test.
The only positive results were as follows:
 
Antiserum
Antigen Ponteves Grand Arbaud Uukuniemi Potepli


* Serum titer/antigen titer; - = <2/<2
Ponteves 128/32 * 16/32 4/16 -
Grand Arbaud 2 /2 64/32 64/8 -
Uukuniemi - 2/8 32/16 64/64
These reactions suggest a relationship between Ponteves and Uukuniemi; and also a one-sided relationship between Ponteves and Grand Arbaud. However, Grand Arbaud is not identical to Uukuniemi.
 
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