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Virus Name:
Powassan
Abbreviation:
POWV
Status
Arbovirus
Select Agent
No
SALS Level
3
SALS Basis
Results of SALS surveys and information from the Catalogue.
Other Information
DOC Permit Required
Antigenic Group
B
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
McLean and Donohue [1]
Antigen of Powassan virus
Immune serum of Powassan virus
Immune sera (guinea pigs) 2 to 4 injs.
HI
CF
NT
Antigens
HI
CF
NT
*
Heterologous/homologous
NT: serum dilution plaque-reduction neutralization titers
Powassan
640
160
100+
Powassan
640
160
100+
St. Louis
320/ND
*
0/160
*
0/400
*
St. Louis
0/160
0/400
Murray Valley
40/ND
0/160
0/1000
Murray Valley
0/160
0/1000
Eastern equine
0/160
0/320
0/100+
Eastern equine
0/320
0/100
Western equine
0/ND
0/20
0/100
Western equine
0/20
0/100
Casals [2]
Antigen of Powassan virus
Immune serum of Powassan virus
Immune sera (mice) several injs
HI
CF
NT
Antigens
HI
CF
NT
*
Heterologous/homologous
NT: serum dilution plaque-reduction neutralization titers.
Powassan
320
128
1000
Powassan
320
128
1000
RSSE
160/5120
*
128/512
*
110/300
*
RSSE
160/5120
32/512
60/300
St. Louis
40/10240
0/512
8/1000
St. Louis
20/10240
4/512
30/1000
Rio Bravo
40/5120+
Rio Bravo
0/5120+
Ilheus
40/5120+
Ilheus
0/5120
Dengue 2
20/2560
Dengue 2
0/2560
Modoc
40/5120+
JBE
40/5120+
Bussuquara
0/320
Banzi
0/2560
In two separate cross-neutralization studies, one involving 42 flaviviruses, Powassan virus could not be placed in a complex [35] ; while the second study concerned 65 flaviviruses and placed Powassan in a complex consisting of 13 other primarily tick-borne flaviviruses [36] .
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