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| | 1. | Antigen (or live virus) and immune serum of registered strain of TBE- RSSE virus regularly gives evidence (in HI, CF, NT or cross-immunity tests) of close antigenic relationship to viruses of Group B tick-borne group including Siberian, Ural and Central European strains of tick-borne encephalitis virus, diphasic milk-borne fever in USSR, Omsk Hemorrhagic Fever (Type I and Type II), louping ill (Scotland), Kyasanur Forest Disease (India), Malayan strain Langat, Japanese strain Negishi, Canadian strain Powassan, and Astrakhan strains from Hyalomma pl. plumbeum ticks. | | 2. | Homologous titer is always higher than heterologous titer in these reactions. | | 3. | Antigen or immune serum of registered strain of TBE-RSSE virus in CF or neutralization tests lack antigenic relationships to viruses of Japanese B encephalitis, West Nile, SLE, EEE, WEE, VEE. | | 4. | Registered strain of virus in HI test (Casals) has antigenic relationship to other members of Group B (including viruses of Japanese B encephalitis, SLE, and West Nile) [15] . | | 5. | Strains of tick-borne encephalitis virus of man in Soviet Far Eastern, Siberian, Ural, Central European and Western European areas occurs in the form of at least two antigenic variants; these are demonstrable only by agar precipitation and specific adsorption mehtod (HI). These antigenic differences are minor [17] . | | 6. | According to Casals by use of hyperimmune sera antigenic relationships to other Group B viruses can be demonstrated. |
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