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No neutralization of San Angelo obtained with WE (1.4 LNI) or SLE (1.7) antisera. No significant neutralization of WE, SLE, ColSK, MM or EMC viruses by San Angelo antiserum (3.8). No HI of WE or SLE viruses by San Angelo antiserum. |
Antigenic relationship [1] with immune sera prepared in guinea pigs by multiple ip injections of active virus (except California, BFS-283; immune rabbit serum used in NT was kindly supplied by Dr. W. McD. Hammon). |
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| San Angelo Virus Antigen |
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| HI | CF | NT |
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Immune Sera or Antigens | Ht/Ho | Ratio | Ht/Ho | Ratio | Ht/Ho |
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| California (BFS-283) | No HA/320 | | 64/256 | 1/4 | 2.9/2.0 | Trivittatus | No HA | | 8/512 | 1/64 | 2.1/4.4 |
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|
| San Angelo Virus Immune Serum |
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| HI | CF | NT |
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Immune Sera or Antigens | Ht/Ho | Ratio | Ht/Ho | Ratio | Ht/Ho |
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|
| California (BFS-283) | 320/No HA | | 64/128 | 1/2 | 4.3/3.8 | Trivittatus | No HA | | 8/64 | 1/8 | 3.3/3.8 |
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Cross CF testing with La Crosse virus and three Texas isolates of California group viruses by Feild, et al. [8] showed the following results. |
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| San Angelo Antigen | San Angelo Immune Serum |
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| CF | CF |
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Immune Sera or Antigens | Ht/Ho | Ht/Ho |
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| NT: LNI in dex | La Crosse | 256/512 | 32/64 | Houston 46713 | 32/128 | 32/64 | San Benito 41079 | 64/64 | 64/64 | Lubbock EM 507 | 256/512 | 64/64 |
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For detailed immunologic comparisons with other members of the California complex, refer to the California encephalitis virus registration card of the Arthropod-borne Information Exchange Catalogue and references [2] , [5] , and [6] . |
SIRACA considers San Angelo virus as a subtype of California encephalitis virus [13] . |
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