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Abbreviations
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Virus Name: Sandfly fever Naples

Abbreviation: SFNV

Status
Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
Phlebotomus Fever

Section VIII - Susceptibility to Experimental Infection (include viremia)

Experimental host and age	Passage history and strain	Inoculation Route-Dose	Evidence of infection	AST (days)	Titer log10/ml


* The original Naples strain was isolated from human serum after a single blind passage (ic) in newborn mice. Initially it produced encephalitis after 14 days; but by the fifth ic passage, the incubation period had decreased to 8 days. By the 35th ic passage, it was lethal ic to weanling mice although the incubation period was longer (18).

Mice (nb)	Prototype	ic 0.01	Death (18)	8	7.8
Mice (nb)	Man 3, SM 5	ip
Mice (nb)		sc
Mice (wn)		ic	No illness (18)
Mice (wn)		ip
Mice (nb)	Man 3, SM 48	ic	Death (6)	5	7.0
hamster(nb)		ic	Death (6)	4-5	6.8

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