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| Apparently identical to Kumba virus [5] , [15] . |
| Indistinguishable by cross-neutralization from Paramaribo virus, but a human Paramaribo convalescent serum in NT with Semliki gave Ht/Ho = 2.8/5.7 [25] . |
| Cross-reactive by HI with other members of Casals' Group A, and sometimes cross-reactive with these by NT, but easily differentiated [15] . |
| Mice immunized with Mayaro or Sindibs [17] or attenuated VEE [7] show significant protection against Semliki challenge. Guinea pigs are protected against small doses of VEE or EEE by 2 (but not 1) doses of Semliki [7] . |
| The course of a human EEE Infection may have been modified by pre-existing Semliki immunity [26] . |
| SIRACA considers Semliki Forest virus to be a distinct virus type in serogroup A [10] ; it is a member of the Semliki complex, one of six complexes comprising serogroup A [10] . |
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