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Virus Name: Semliki Forest

Abbreviation: SFV

Status
Arbovirus

Select Agent
No

SALS Level
3

SALS Basis
Fatal human laboratoryinfection, 1978, probably aerosol. This is recognized to be a unique incident in a long history of work with SFV under minimal biocontainment conditions. However, since the virulence characteristics of the strain responsible in this case require further study and the prevalence of subclinical infections in laboratories working with SFV remains unknown, the committee recommends Level 3 until further information is available warranting reconsideration at a lower level.

Other Information

Antigenic Group
A

Section IX - Experimental Arthropod Infection and Transmission

Arthropod species & virus source(a)	Method of Infection log10/ml (b)		Incubation period (c)		Transmision by bite (d)		Assay of arthropod, log10/ml (e)
	Feeding	Injected	Days	°C	Host	Ratio	Whole	Organ	System


Serial salivary gland passage after parenteral inoculation achieved with Ae aegypti, An quadrimaculatus, Cx quinquefasciatus, Cx salinarius (37), Cx tarsalis, Ornithodoros savignyi and larval insects.
Transmitted by Ae aegypti, Ae togoi, An albimanus, An quadrimaculatus.

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