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Virus Name: Sepik

Abbreviation: SEPV

Status
Probable Arbovirus

Select Agent
No

SALS Level
3

SALS Basis
Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.

Other Information

Antigenic Group
B

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

	Sepik (MK 7148) Antigen			Sepik (MK 7148) Antiserum
	HI	CF	NT	HI	CF	NT
Mouse Immune Ascitic Fluids or Antigens	Ht/Ho	Ht/Ho	Ht/Ho	Ht/Ho	Ht/Ho	Ht/Ho


NT: LNI in dex.
^* Tests from Apoi down were carried out at YARU by Dr. G.M. Woodroofe
MVE	480/10240	5/80	1.0/5.0	320/320	<5/320	1.3/5.0
Kokobera	<10/1280	<5/40	0.7/3.0	160/320	5/320	0.5/5.0
Kunjin	1280/10240	<5/40	0.7/4.3	320/320	<5/320	0.5/5.0
Edge Hill	<10/320	20/320	0.4/1.0	160/320	10/320	0.5/5.0
Stratford	<10/20	<5/40	<0.5/0.7	120/320	<5/320	<0.5/5.0
JBE	640/1280	<5/160		40/320	<5/320
Apoi ^*		<4/32			8/1024
Langat		<4/32			8/1024
Tembusu		16/512			16/1024
Zika		4/32			4/1024
Wesselsbron		8/8	2.7/4.5		512/1024	3.1/>4.5
West Nile		16/512			16/1024
Dengue 1		<4/32			<4/1024
Dengue 2		<4/32			<4/1024
Dengue 3		4/4			<4/1024
Dengue 4		<4/4			16/1024

Sepik virus is closely related to Wesselsbron virus but distinguishable by neutralization test from both South African and Thai strains of that virus.

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