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Virus Name: Snowshoe hare

Abbreviation: SSHV

Status
Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
California

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

Neutralization (weaned mice ic) [2]				Hemagglutination inhibition [2]
	Antiserum				Antiserum
Virus	SSH	LAC	CE	Antigen	SSH	LAC	CE


^a Neutralization index in dex.
SSH	5.5 ^a	4.2	4.3	SSH	1280	320	80
LAC	3.4	4.0	3.0	LAC	320	640	80
CE	2.0	3.9	3.7	CE	640	320	320

Complement fixation [2]
	Antiserum ^b
Antigen	CE	SSH	LAC	TVT	KEY	JS	SA	JC	TAH	LUM	MEL	GRO


^b Antiserum titer in presence of optimal dilution of antigen; multiple injection mouse antiserum.
CE	128	32	16	4	16	32	32	8	32	64	16	0
SSH	64	256	32	8	64	32	32	8	64	128	16	0
LAC	32	64	64	8	64	32	16	8	32	32	8	0
TVT	8	16	4	128	16	16	8	0	16	16	8	0
KEY	64	32	16	16	128	64	32	16	64	64	64	0
JS	32	16	8	4	32	256	16	16	32	32	16	0
SA	32	32	8	0	8	32	64	4	32	32	8	0
JC	32	16	16	4	32	32	16	64	16	32	16	0
TAH	32	128	16	0	64	32	32	4	256	128	8	0
LUM	32	64	8	0	32	32	16	4	64	128	8	0
MEL	32	16	8	0	32	64	16	4	16	64	256	0
GRO	0	0	0	0		0	0	0	0	0	0	256

Plaque reduction neutralization [3]
	Antiserum
Virus	CE	SSH	JC	LAC	KEY


^c Reciprocal of serum dilution giving 90% reduction.
CE	10240 ^c	2560	80	2560	40
SSH	320	20480	160	2560	10
JC	320	160	20480	1280	20
LAC	40	1280	<10	1280	10
KEY	20	80	20	20	160

SIRACA considers snowshoe hare virus to be a variety of La Crosse virus.

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