| | | | | Cell system (a) | Virus passage history (b) | Evidence of Infection | | |
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| | CPE | PLAQUES | Growth Without CPE | | |
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| | Day (c) | Extent (d) | Titer TCD50/ml (e) | Day (c) | Size (f) | Titer PFU/ml (e) | +/- (g) | | |
|---|
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| | SLE virus produces CPE and plaques in various continuous and primary cell culture systems. Cell cultures derived from human, primate, rodent, swine and avian tissues and invertebrate cell cultures support the multiplication of SLE virus with or without CPE. SLE virus has produced CPE in primary chick embryo, duck (questionable) and hamster kidney cell cultures; in HeLa human amnion, human epithelial-like, BHK-21, Vero, PS; and plaques in KB, BHK-21, Vero, LLC-MK2, MA-104, BS-C-1, and PS continuous cell cultures. Plaques also were produced in primary chick embryo and duck kidney cell cultures (40). | | |
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