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  Sunday Canyon   SCAV

Possible Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Ungoruped
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
No serological relationship to any of 196 strains of arboviruses or 20 other viruses, mostly murine [1] .
In CF tests hyperimmune sera or ascitic fluids prepared in mice against Sunday Canyon virus did not react with any of 139 virus antigens of diverse origin. In other CF tests, potent Sunday Canyon virus antigens failed to fix complement in the presence of hyperimmune fluids prepared against 177 viruses or of 6 pools of sera randomly selected at various times from the Rocky Mountain Laboratory (RML) normal mouse colony. Included in these tests were 25 polyvalent grouping antisera known to be reactive with all viruses of a given serological group * or with the nominal viruses (CF results mainly from L. Thomas, RML and J. Casals, YARU).
In NT tests, suckling mice were not protected from ic inoculation of Sunday Canyon virus after its incubation with hyperimmune serum from 16 tick-borne viruses: Farallon, Hughes, Huacho, Johnston Atoll, Kemerovo, Mono Lake, Nyamanini, Punta Salinas, Quaranfil, Raza, Sapphire I, Sapphire II, Sixgun City, Tyuleniy, Yaquina Head, and Zirqa. In Vero cells, Sunday Canyon plaques were not reduced by prior incubation of the virus with potent antisera prepared against Hughes, Punta Salinas, Sapphire II, Sixgun City and Yaquina Head viruses.
In "mouse antibody production tests" performed at Microbiological Associates by J. Parker, known-virus free mice inoculated with Sunday Canyon virus failed to respond with CF or HI antibodies against 12 murine viruses: ectromelia, GDVII, K, LCM, LDH **, minute virus of mice, mouse hepatitis, mouse pneumonia, murine adenovirus, polyoma, reovirus-3, and Sendai.

* Groups A, C, BUN, CAL, CAP, GMA, KEM, PHL, SIM, TCR, TETE, VSV
** lactic dehydrogenase virus
 
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