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Virus Name:
Tacaribe
Abbreviation:
TCRV
Status
Not Arbovirus
Select Agent
No
SALS Level
2
SALS Basis
Level 2 arenaviruses are not known to cause serious acute disease in man and are not acutely pathogenic for laboratory animals, including primates. Survey experience is sufficient to conclude that laboratory aerosol infection does not occur in the course of routine work with cell cultures and animals not subject to chronic infection. In view of reported high frequency of laboratory aerosol infection that occurred in workers manipulating high concentrations of Pichinde virus, it is strongly recommended that work with high concentrations of Level 2 arenaviruses be done at Level 3.
Other Information
Antigenic Group
Tacaribe
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
Tacaribe virus is antigenically related to Junin virus [2] and more recently a third virus, Machupo, the agent of Bolivian hemorrhagic fever, has been found related to both Tacaribe and Junin. The name Tacaribe has been applied to this group or complex [3] . For information on this relationship consult Junin and Machupo Catalogue cards.
For list of viruses with which antigenic comparison has been made with negative results see Reference [1] .
Tacaribe group viruses shown to be related serologically to LCM virus ahd have been placed in Arenavirus group [2] , [8] .
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