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Virus Name: Tacaribe

Abbreviation: TCRV

Status
Not Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Level 2 arenaviruses are not known to cause serious acute disease in man and are not acutely pathogenic for laboratory animals, including primates. Survey experience is sufficient to conclude that laboratory aerosol infection does not occur in the course of routine work with cell cultures and animals not subject to chronic infection. In view of reported high frequency of laboratory aerosol infection that occurred in workers manipulating high concentrations of Pichinde virus, it is strongly recommended that work with high concentrations of Level 2 arenaviruses be done at Level 3.

Other Information

Antigenic Group
Tacaribe

Section VII - Natural Host Range (Additional text can be added below table)

Vertebrate (species and organ) and arthropod	No. isolations/No. tested	No. with antibody/No. tested Test used	Country and region


NT: Technical difficulties with the NT (variable and low virus titers) have delayed studies of immunity in vertebrates.

Man	0/2,500		Trinidad
Cebus apella (monkey)	0/26
Alouatta (monkey)	0/79
Birds	0/2,300
Sentinel mice	0
Artibeus jamaicensis trinitatis	9/242	0/8 NT	Port of Spain, Trinidad (1)
Artibeus lituratus palmarum	10/140	0/4 NT
Desmodus rotundus	0/148	0/5 NT
Other species of bats	0/320
Bats (25 species)		15/101 NT	Trinidad (10)
Mixed mosquito pool	1/344		Rio Grande Forest, Trinidad

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