| | | Serological relationships (CF test). | | Comparison to other European tick-borne viruses: | | | | Antigen | Serum titer |
|---|
| | 63a | 225 | Uukuniemi | Tribec | CEE | Kemerovo | Bhanja |
|---|
|
| | 0 = negative: blank = not tested | | 63a | 16 | 0 | 0 | 0 | 0 | 0 | 0 | | 225a | 8 | 8 | 0 | 0 | | | | Uukuniemi | 0 | | 128 | | | | | Tribec | 0 | | | 16 | | | | CEE | 0 | | | | 64 | |
| | Studies at YARU have shown that strain 63 is indistinguishable, by complement fixation test, from another strain, Art 1147 ** previously received from NAMRU-3, Cairo, isolated by the staff of that laboratory. Both virus strains, 63 and Art 1147, were compared by complement-fixation test with a large number of tick-borne viruses not of group B: Immune sera against both strains reacted negatively with the following antigens; Bandia, Bhanja, Chenuda, Colorado tick fever, Crimean hemorrhagic fever-Congo, DGK, Dhori, Dugbe, Farallon, Ganjam, Grand Arbaud, Hazara, Huacho, Hughes, Johnston Atoll, Kaisodi, Kemerovo, Lanjan, Lipovnik, Lone Star, Keterah, Manawa, Matucare, Mono Lake, Nyamanini, Qualyub, Quaranfil, Sawgrass, Silverwater, Soldado, Thogoto, Tribec, Upolu, Uukuniemi, Wad Medani, Zirqa, Jos, Punta Salinas, Kao Shuan and Pathum Thani. | | The homologous titers of the strains 63 and Art 1147 antisera used at YARU were between 1:64 and 1:128. | | Prototype Tettnang virus was found to cross-react with mouse hepatitis virus by complement-fixation tests. This observation was independently confirmed by Dr. J. Casals [4] . There are two possible interpretations of these observations: 1) Prototype Tettnang virus is mouse hepatitis virus or closely related to mouse hepatitis virus. 2) Tettnang virus has been contaminated with mouse hepatitis virus subsequent to its isolation. (ed.) | | The antigenic relationship of Tettnang virus strains to mouse hepatitis virus strains was confirmed by NT [6] . |
** Art 1147 was isolated from Hyalomma dromedarii ticks taken from a camel in Egypt. (J. Casals, personal communication). | | |
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