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Virus Name: Umatilla

Abbreviation: UMAV

Status
Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
*

Section VIII - Susceptibility to Experimental Infection (include viremia)

Experimental host and age	Passage history and strain	Inoculation Route-Dose	Evidence of infection	AST (days)	Titer log10/ml


** Virus remained nonpathogenic for suckling mice and suckling hamsters through 5 blind passages (ic). Virus (2.0 to 4.0 dex PFU/ml) was demonstrable in brain harvests at each passage level.

Mice (nb)**		ic	None
Mice (nb)		ip	None
Mice (nb)		sc
Mice (wn)		ic
Mice (wn)		ip	None
hamsters** (nb)		ic	Sporadic deaths,probably
			nonspecific
hamsters (2 wk)		ic	None
guinea pigs (1-3 day)		ic	None
rabbits (2-4 mo)		im	Antibody production
chickens (1-2 day)		sc	Viremia, no illness 0.1 ml inoculum contained 2.7 dex PFU. On 8th day post-inoculation, the 3 chicks inoculated had viremias, respectively of 3.8, 1.4, and 2.5 dex PFU/0.1 ml of whole blood. Maximum titer, 43 hours = 6.0 dex PFU/ml.

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