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Arbovirus Catalog

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Virus Sections

Virus Name/Prototype
Original Source
Method of Isolation
Virus Properties
Antigenic Relationship
Biologic Characteristics
Natural Host Range
Susceptibility to...
Experimental Infection...
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  Yellow fever   YFV

Arbovirus

No

3

Results of SALS surveys and information from the Catalogue.
Other Information
DOC Permit Required, Hepa Filtration, Vaccination Recommended 

B
Section IV - Virus Properties
Physicochemical
RNA, Single Strand
 


Yes

RNA=3.75 x 106 daltons (24)(S)




3

Nucleocapsid; major virion envelope protein (usually glycosolated); nonglycosolated virion envelope protein (24).The complete nucleotide sequence for the RNA genome of yellow fever virus has been determined (24).




(S)


(S)

Stability of Infectivity (effects)


25%

Reduced 3 dex





1:1000

2.8 dex

6.9 dex

Inactivated by trypsin

Virion Morphology


22-38; 30-40 nm

nm

nm

Filtration, electon microscopy

Envelope observed


Morphogenesis






Hemagglutination

Yes

SMB; monkey serum; tissue cultures ext. by sucrose-acetone; acetone-ether; fluorocarbon-borate saline

Goose

5.8-6.6

6.2

4dC - 37dC

22dC

(a) Fever = 103/F, severe headache, backache, prostration; symptoms subsided after 48 hours.

HI, CF, NT, IFA

(a) Fever = 103/F, severe headache, backache, prostration; symptoms subsided after 48 hours.
 
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