Physicochemical
RNA, Single Strand
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Yes
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RNA=3.75 x 106 daltons (24)(S)
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3
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Nucleocapsid; major virion envelope protein (usually glycosolated); nonglycosolated virion envelope protein (24).The complete nucleotide sequence for the RNA genome of yellow fever virus has been determined (24).
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(S)
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(S)
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| Stability of Infectivity (effects) |
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25%
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Reduced 3 dex
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1:1000
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2.8 dex
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6.9 dex
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Inactivated by trypsin
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| Virion Morphology |
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22-38; 30-40 nm
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nm
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nm
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Filtration, electon microscopy
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Envelope observed
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| Morphogenesis |
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| Hemagglutination |
Yes
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SMB; monkey serum; tissue cultures ext. by sucrose-acetone;
acetone-ether; fluorocarbon-borate saline
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Goose
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5.8-6.6
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6.2
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4dC - 37dC
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22dC
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(a) Fever = 103/F, severe headache, backache, prostration; symptoms subsided
after 48 hours.
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HI, CF, NT, IFA
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(a) Fever = 103/F, severe headache, backache, prostration; symptoms subsided
after 48 hours.
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