| | | | | Experimental host and age | Passage history and strain | Inoculation Route-Dose | Evidence of infection | AST (days) | Titer log10/ml | |
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| | Most strains have not killed adult mice until after 2 or 3 suckling passages or one rhesus monkey passage. After 100 ic passages in mice, the prototype lost most ip virulence (1). | | Mice (nb) | SMB 14 | ic 0.01 | Death | 2 | 11.0 | | | Mice (nb) | | ip in,sc | Death | | | | | Mice (nb) | | sc | | | | | | Mice (wn) | | ic 0.03 | Paralysis, death | 3-17 | 7.0 | | | Mice (wn) | | ip | Paralysis, death | 5-12 | 4.0 | | | albino rats | | ic | Antibody | | | | | hamsters | | ic or sc | Fatal encephalitis | | | | | rabbits | | ic or sc | Antibody | | | | | guinea pigs | | ic or ip | Antibody | | | | | rhesus monkeys | | sc | Viremia, antibody; 1/3 died (1) | | | | | lambs | | | Antibody (21) | | | | | man (ad) | | iv 500 | Severe encephalitis (only 1/3 infected) (18) | | | | | Cercopithecus | | ic | Viremia, antibody (2) | | | | | wild rodents(ad) | | sc or ip | Viremia, antibody (14,19) | | | | | | | | | | | | | | | | | | | | | | | | | | | |
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