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  Bunyamwera   BUNV

Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Bunyamwera
Section VIII - Susceptibility to Experimental Infection (include viremia)
 
 
Experimental host and age Passage history and strain Inoculation Route-Dose Evidence of infection AST (days) Titer log10/ml


Most strains have not killed adult mice until after 2 or 3 suckling passages or one rhesus monkey passage. After 100 ic passages in mice, the prototype lost most ip virulence (1).
Mice (nb) SMB 14 ic 0.01 Death 2 11.0
Mice (nb) ip in,sc Death
Mice (nb) sc
Mice (wn) ic 0.03 Paralysis, death 3-17 7.0
Mice (wn) ip Paralysis, death 5-12 4.0
albino rats ic Antibody
hamsters ic or sc Fatal encephalitis
rabbits ic or sc Antibody
guinea pigs ic or ip Antibody
rhesus monkeys sc Viremia, antibody; 1/3 died (1)
lambs Antibody (21)
man (ad) iv 500 Severe encephalitis (only 1/3 infected) (18)
Cercopithecus ic Viremia, antibody (2)
wild rodents(ad) sc or ip Viremia, antibody (14,19)
 
 
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