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Data last updated: 06/28/23
199720211997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021
Hemolytic Uremic Syndrome (HUS)
Cases
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1,624
cases
0.6
incidence per 100,000 children
Hospitalizations
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11 days
median days of hospitalization
0 to 372
range of hospitalization days
Deaths
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38
deaths
2.3%
of HUS patients died
Incidence per 100,000 of post-diarrheal HUS in children by year for FoodNet sites
00.20.40.60.81.0Incidence per 100,000 children1997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021
Percentage of pediatric, post-diarrheal HUS patients by month for FoodNet sites
2%4%6%8%10%12%14%16%18%Percentage of HUS patientsJanuaryFebruaryMarchAprilMayJuneJulyAugustSeptemberOctoberNovemberDecember
Seasonality data are not displayed for all FoodNet sites. As a result, totals for this figure may not match totals displayed in other parts of FoodNet Fast. Users should be aware of this limitation before using these data for analysis.
Incidence per 100,000 of post-diarrheal HUS in children by age group and sex for FoodNet sites
00.250.500.751.001.251.50Incidence per 100,000 child...<55-910-17
00.20.40.60.8Incidence per 100,000 child...MaleFemale
Percentage of pediatric, post-diarrheal HUS patients in FoodNet sites having evidence of STEC, by year
0%20%40%60%80%100%Percentage of HUS cases1997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021Evidence of STECNo evidence of STEC

Percentage of pediatric, post-diarrheal HUS patients, by laboratory testing method used
Culture-confirmed 61%Shiga toxin-positive only 5%Serology-positive 8%No evidence of STEC 26%
Number of HUS patients among those with culture-confirmed STEC infection, by serogroup
O130O141O146O175O2O45O71O98O103O157 and non-O157†O26O121UndeterminedO145O111O157STEC serogroups024681012141618202224900902904
* Evidence of STEC includes cases that are culture-confirmed, serology-positive, or Shiga toxin-positive only.
† O157 and non-O157 includes cases that are confirmed to have O157 and one or more non-O157 serogroups.
‡ Multiple non-O157 includes any combination of non-O157 serogroups.
Evidence of STEC includes all HUS cases that have tested positive for STEC by one or more methods of testing. Shiga toxin-positive only includes testing by Immunoassay and/or PCR for Shiga toxin or the genes that produce it. The pie graph breaks down evidence of STEC by testing method and no evidence. These designations are mutually exclusive; therefore,
  • Culture-confirmed: shows the percentage of patients who tested positive for STEC infection by culture. Culture-positive STEC infections are Shiga toxin-positive. Patients may also be positive for STEC O157 by serology.
  • Serology-positive: shows the percentage of patients who tested positive for STEC O157 by serology. These patients do not have a culture-confirmed STEC infection but they may have tested positive for Shiga toxin by other methods.
  • Shiga toxin-positive only: shows the percentage of patients who tested positive for Shiga toxin.
  • No evidence of STEC: shows the percentage of HUS patients who did not test positive for STEC infections. This includes patients who were not tested for STEC infection or who tested negative for STEC infection.
The bar graph displays the serogroups identified for culture-confirmed cases.
Incidence per 100,000 children of HUS and confirmed STEC O157 and non-O157 infections by year for FoodNet sites
FoodNet pathogen surveillance data

Confirmed infections of STEC O157 and non-O157 in children (right axis) from FoodNet pathogen surveillance and postdiarrheal HUS (left axis) in children from HUS surveillance

199719981999200020012002200320042005200620072008200920102011201220132014201520162017201820192020202100.20.40.60.81.0HUS Incidence per 100,000 chil...0246810STEC Incidence per 100,000 chil...STEC O157STEC NON-O157HUS
Incidence per 100,000 children of post-diarrheal HUS from HUS surveillance (left axis) and in confirmed infections of STEC O157 and non-O157 (right axis) from pathogen surveillance in FoodNet sites