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Trends in Prevalence of Polycystic Kidney Disease in the Military Health System

Trends in Prevalence of Polycystic Kidney Disease in the Military Health System

The crude prevalence of Military Health System (MHS) beneficiaries with PKD ranged from 58 per 100,000 beneficiaries in 2016–2018 to 54 per 100,000 beneficiaries in 2019–2021. Prevalence of PKD was highest among adults aged ≥70 years for both time periods but higher for 2016–2018. Crude prevalence was highest among females. Crude and age-adjusted prevalence was highest among Black adults. Across all sex and race and ethnicity groups, prevalence was highest for 2016–2018.

Data Source: MHS

To view trends in prevalence of PKD in the MHS by risk categories, select from the drop-down menu below. Risk categories include Overall, Age Category, Sex, and Race/Ethnicity.


PKD Prevalence per 100,000, Overall

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Estimates were standardized to the 2010 U.S. Census population.

The Military Health System (MHS) provides comprehensive primary and specialty care for more than 9.6 million active-duty personnel and military retirees and their families worldwide. The MHS Data Repository (MDR) is the administrative claims database for all care received through MHS, including direct care received in military treatment facilities and purchased care received in civilian treatment facilities. The MDR does not capture health care delivery in combat zones or care received in the VHA system. All patients were in the TRICARE Prime managed care option. Data are from both the direct care (military facilities) and private care (private facilities through TRICARE coverage) systems.

De-identified patient data were obtained from the MHS data repository. Data contain both the estimated glomerular filtration rate (eGFR) definition of chronic kidney disease (CKD) and claims-based CKD defined by using ICD-9-CM and ICD-10-CM codes diagnosis codes with at least one inpatient or two outpatient CKD diagnoses. To be included in analyses, service members and their dependents had to have at least one inpatient or outpatient record during the fiscal year (October 1 to September 30). Data cells with 10 or fewer patients were suppressed.

Disclaimer: The views expressed are those of the authors and do not reflect the official policy of the Uniformed Services University, Departments of Army/Navy/Air Force, Department of War, Centers for Disease Control and Prevention, Department of Health and Human Services, or US government.

FieldData
Description of Measure

Three-year prevalence period of MHS beneficiaries with diagnosed polycystic kidney disease (PKD).

Data Set

Source files from MHS Data Repository (MDR).

ICD Coding: GENESIS Encounter (BDE 3.0, direct care), GENESIS Admission Table (BDE 3.0, direct care), CAPER (direct care outpatient claims), SIDR (direct care inpatient claims), TED-NI (private care outpatient claims), TED-I Header (private care inpatient claims).

Laboratories: CDR Chemistry, SIDR, CADRE Laboratory Enhanced, GENESIS Laboratory Results (BDE 3.0), TED-NI (private-sector laboratory claims).

Demographics: VM6BEN (demographic information from the Defense Enrollment Eligibility Reporting System), GENESIS Person (BDE 3.0).

Medications: PDTS (Pharmacy Data Transaction Service).

BDE: Bulk Data extract, CADRE: Comprehensive Ancillary Data Record Extract, CAPER: Comprehensive

Ambulatory/Professional Encounter Record, CDR: Clinical Data Repository, GENESIS:  name of the MHS EHR, SIDR: Standard Inpatient Data Record, TED-I: TRICARE Encounter Data – Institutional, TED-NI: TRICARE Encounter Data – Non-Institutional.

Population

Beneficiaries of all ages enrolled in the TRICARE Prime or Plus managed care options.

Years Included

Fiscal years 2016−2021 (October 1, 2015, to September 30, 2021). The analyses were divided into two three-year periods, 2016–2018 and 2019–2021.

Numerator

The number of beneficiaries in the denominator with ICD-10 code for PKD. Data cells with less than 11 counts were suppressed.

Denominator

Population enrolled in Defense Enrollment Eligibility Reporting System (DEERS) in the midpoint year of each wave (i.e., 2017 and 2020).

Definition of PKD

Presence of one ICD-10 code for PKD for an evaluation and management (E/M) encounter with a physician, nurse practitioner, or physician assistant, in any of the three years of the wave.

ICD-10 Codes

Q612 (polycystic kidney disease, autosomal dominant) and Q613 (polycystic kidney disease, unspecified).

Dialysis and Transplant

Beneficiaries with encounters with ICD-9 or ICD-10 or CPT codes for dialysis or transplant were included.

Age Standardization

Estimates were standardized to the 2010 U.S. Census population for adults: 18–39 years: 37.1%, 40–59 years: 38.1%, 60–69 years: 12.8%, and 70+ years: 12.0%. Age-standardized prevalence excluded pediatric numbers.

Limitations of Indicator

PKD is captured by ICD diagnosis codes from claims and coding data and does not include results from imaging tests, genetic testing, or laboratory evaluation.

Analytical Considerations

For PKD, it should be noted that ascertainment using claims data can be low. Active-duty service members constitute around 43% of MHS beneficiaries and tend to be younger and healthier than the general population.

Disclaimer

The contents of this publication are the sole responsibility of the authors and do not necessarily reflect the views, assertions, opinions, or policies of the Uniformed Services University of the Health Sciences, the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., the Departments of the Army, Navy, or Air Force, or the Department of Health and Human Services.


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