Toxicological Profile for Toluene Diisocyanate and Methylenediphenyl Diisocyanate
Toxicological Profile Information
The ATSDR toxicological profile succinctly characterizes the toxicologic and
adverse health effects information for the hazardous substance described
here. Each peer-reviewed profile identifies and reviews the key literature
that describes a hazardous substance's toxicologic properties. Other
pertinent literature is also presented, but is described in less detail than
the key studies. The complete list of topics covered (chapter titles) is
shown at the left and in more detail further down this page.
The focus of the profile is on health and toxicologic information. Therefore,
each profile begins with a Public Health Statement that summarizes in nontechnical language, a substance's relevant properties.
A useful two page information sheet, the ToxFAQsTM,
is also available.
Toxicological Profile Access
In order to access the ATSDR toxicological profile PDF files below, you must have Adobe Acrobat Reader. You may download that program free from Adobe.
Complete Profilepdf icon[PDF - 7.91 MB]
Prefacepdf icon[PDF - 859 KB]
1. Public Health Statementpdf icon[PDF - 1.01 MB]
2. Relevance to Public Healthpdf icon[PDF - 1.05 MB]
3. Health Effectspdf icon[PDF - 5.91 MB]
4. Chemical and Physical Informationpdf icon[PDF - 902 KB]
5. Production, Import, Use, and Disposalpdf icon[PDF - 965 KB]
6. Potential for Human Exposurepdf icon[PDF - 1.08 MB]
7. Analytical Methodspdf icon[PDF - 926 KB]
8. Regulations, Advisories, and Guidelinespdf icon[PDF - 890 KB]
9. Referencespdf icon[PDF - 676 KB]
10. Glossarypdf icon[PDF - 951 KB]
Appendicespdf icon[PDF - 907 KB]
Agency for Toxic Substances and Disease Registry (ATSDR). 2018. Toxicological
profile for Toluene Diisocyanate. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.
All ATSDR toxicological profile PDF files are electronic conversions from other electronic text files. This conversion may have resulted in character translation or format errors.
Regulations or guidelines may change. Please check with the appropriate agency for any changes to the regulations or guidelines cited.
Where can I get more information?
If you have questions or concerns, please contact your community or state health or environmental quality department or:
For more information, contact:
Agency for Toxic Substances and Disease Registry
Office of Innovation and Analytics, Toxicology Section
4770 Buford Highway
Chamblee, GA 30341-3717
Phone: 1-800-CDC-INFO 888-232-6348 (TTY)
Email: Contact CDC-INFO
ATSDR can also tell you the location of occupational and environmental health clinics. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances.