Minimal Risk Levels for Hazardous Substances

Minimal Risk Levels (MRLs) for Hazardous Substances

MRLs in draft Toxicological Profiles are provisional.
See bottom of table for more information.

ATSDR Minimal Risk Levels (MRLs) - August 2022
Route	Duration	MRL	Factors*	Endpoint	Draft/ Final	Cover Date	CAS Number

ACENAPHTHENE
Oral	Int.	0.6 mg/kg/day	300	Hepatic	Final	08/1995	83-32-9

ACETONE
Inh.	Acute	8 ppm	30	Neurol.	Final	06/2022	67-64-1
Oral	Int.	0.6 mg/kg/day	100	Hemato.	Final	06/2022	67-64-1

ACROLEIN
Inh.	Acute	0.003 ppm	100	Resp.	Final	08/2007	107-02-8
Inh.	Int.	0.00004 ppm	300	Resp.	Final	08/2007	107-02-8
Oral	Int.	0.004 mg/kg/day	100	Gastro.	Final	08/2007	107-02-8

ACRYLAMIDE
Oral	Acute	0.01 mg/kg/day	30	Repro.	Final	12/2012	79-06-1
Oral	Int.	0.001 mg/kg/day	30	Neurol.	Final	12/2012	79-06-1
Oral	Chr.	0.001 mg/kg/day	30	Neurol.	Final	12/2012	79-06-1

ACRYLONITRILE
Inh.	Acute	0.1 ppm	10	Neurol.	Final	12/1990	107-13-1
Oral	Acute	0.1 mg/kg/day	100	Develop.	Final	12/1990	107-13-1
Oral	Int.	0.01 mg/kg/day	1000	Repro.	Final	12/1990	107-13-1
Oral	Chr.	0.04 mg/kg/day	100	Hemato.	Final	12/1990	107-13-1

ALDRIN
Oral	Acute	2 ug/kg/day	1000	Develop.	Final	06/2022	309-00-2
Oral	Chr.	0.04 ug/kg/day	1000	Hepatic	Final	06/2022	309-00-2

ALUMINUM
Oral	Int.	1 mg/kg/day	30	Neurol.	Final	09/2008	7429-90-5
Oral	Chr.	1 mg/kg/day	90	Neurol.	Final	09/2008	7429-90-5

AMERICIUM
Rad.	Acute	4 mSv	3	Develop.	Final	04/2004	7440-35-9
Rad.	Chr.	1 mSv/yr	3	Other	Final	04/2004	7440-35-9

AMMONIA
Inh.	Acute	1.7 ppm	30	Resp.	Final	09/2004	7664-41-7
Inh.	Chr.	0.1 ppm	30	Resp.	Final	09/2004	7664-41-7

ANTHRACENE
Oral	Int.	10 mg/kg/day	100	Hepatic	Final	08/1995	120-12-7

ANTIMONY
Inh	Acute	0.001 mg/m3	30	Resp.	Final	10/2019	7440-36-0
Inh.	Int.	0.001 mg/m3	30	Resp.	Final	10/2019	7440-36-0
Inh.	Chr.	0.0003 mg/m3	30	Resp.	Final	10/2019	7440-36-0
Oral	Acute	1 mg/kg/day	100	Hepatic	Final	10/2019	7440-36-0
Oral	Int.	0.0006 mg/kg/day	100	Metab.	Final	10/2019	7440-36-0

ARSENIC
Oral	Acute	0.005 mg/kg/day	10	Gastro.	Final	08/2007	7440-38-2
Oral	Chr.	0.0003 mg/kg/day	3	Dermal	Final	08/2007	7440-38-2

ATRAZINE
Oral	Acute	0.01 mg/kg/day	100	Body Wt.	Final	09/2003	1912-24-9
Oral	Int.	0.003 mg/kg/day	300	Repro.	Final	09/2003	1912-24-9

1-BROMOPROPANE
Inh.	Acute	1 ppm	30	Neurol.	Final	08/2017	106-94-5
Inh.	Int.	0.1 ppm	30	Neurol.	Final	08/2017	106-94-5
Inh.	Chr.	0.02 ppm	30	Neurol.	Final	08/2017	106-94-5
Oral	Acute	0.2 mg/kg/day	100	Neurol.	Final	08/2017	106-94-5

2-BUTANONE
Inh.	Acute	1 ppm	100	Neurol.	Final	10/2020	78-93-3

2-BUTOXYETHANOL
Inh.	Acute	6 ppm	9	Hemato.	Final	08/1998	111-76-2
Inh.	Int.	3 ppm	9	Hemato.	Final	08/1998	111-76-2
Inh.	Chr.	0.2 ppm	3	Hemato.	Final	08/1998	111-76-2
Oral	Acute	0.4 mg/kg/day	90	Hemato.	Final	08/1998	111-76-2
Oral	Int.	0.07 mg/kg/day	1000	Hepatic	Final	08/1998	111-76-2

BARIUM, SOLUBLE SALTS
Oral	Int.	0.2 mg/kg/day	300	Renal	Final	08/2007	7440-39-3
Oral	Chr.	0.2 mg/kg/day	300	Renal	Final	08/2007	7440-39-3

BENZENE
Inh.	Acute	0.009 ppm	300	Immuno.	Final	08/2007	71-43-2
Inh.	Int.	0.006 ppm	300	Immuno.	Final	08/2007	71-43-2
Inh.	Chr.	0.003 ppm	10	Immuno.	Final	08/2007	71-43-2
Oral	Chr.	0.0005 mg/kg/day	30	Immuno.	Final	08/2007	71-43-2

BERYLLIUM
Inh.	Int.	1 ng/m3	30	Resp.	Draft	01/2022	7440-41-7

BIS(2 CHLOROETHYL)ETHER (BCEE)
Inh.	Int.	0.02 ppm	1000	Body Wt.	Final	10/2017	111-44-4

BIS(CHLOROMETHYL)ETHER (BCME)
Inh.	Int.	0.0003 ppm	100	Resp.	Final	11/2017	542-88-1

BORON AND COMPOUNDS
Inh.	Acute	0.3 mg/m3	3	Resp.	Final	11/2010	7440-42-8
Oral	Acute	0.2 mg/kg/day	100	Develop.	Final	11/2010	7440-42-8
Oral	Int.	0.2 mg/kg/day	66	Develop.	Final	11/2010	7440-42-8

BROMODICHLOROMETHANE
Oral	Acute	0.07 mg/kg/day	100	Develop.	Final	03/2020	75-27-4
Oral	Chr.	0.008 mg/kg/day	100	Hepatic	Final	03/2020	75-27-4

BROMOFORM
Oral	Acute	0.7 mg/kg/day	100	Hepatic	Final	08/2005	75-25-2
Oral	Int.	0.2 mg/kg/day	100	Hepatic	Final	08/2005	75-25-2
Oral	Chr.	0.02 mg/kg/day	3000	Hepatic	Final	08/2005	75-25-2

BROMOMETHANE
Inh.	Int.	0.02 ppm	90	Neurol.	Final	03/2020	74-83-9
Inh.	Chr.	0.001 ppm	90	Resp.	Final	03/2020	74-83-9

2-CHLOROPHENOL
Oral	Int.	0.08 mg/kg/day	100	Reprod.	Final	06/2022	95-57-8

4-CHLOROPHENOL
Oral	Int.	0.9 mg/kg/day	100	Reprod.	Final	06/2022	106-48-9

CADMIUM
Inh.	Acute	0.00003 mg/m3	300	Resp.	Final	09/2012	7440-43-9
Inh.	Chr.	0.00001 mg/m3	9	Renal	Final	09/2012	7440-43-9
Oral	Int.	0.0005 mg/kg/day	100	Musculo.	Final	09/2012	7440-43-9
Oral	Chr.	0.0001 mg/kg/day	3	Renal	Final	09/2012	7440-43-9

CARBON DISULFIDE
Inh.	Chr.	0.3 ppm	30	Neurol.	Final	08/1996	75-15-0
Oral	Acute	0.01 mg/kg/day	300	Hepatic	Final	08/1996	75-15-0

CARBON TETRACHLORIDE
Inh.	Int.	0.03 ppm	30	Hepatic	Final	08/2005	56-23-5
Inh.	Chr.	0.03 ppm	30	Hepatic	Final	08/2005	56-23-5
Oral	Acute	0.02 mg/kg/day	300	Hepatic	Final	08/2005	56-23-5
Oral	Int.	0.007 mg/kg/day	100	Hepatic	Final	08/2005	56-23-5

CESIUM
Rad.	Acute	4 mSv	3	Develop.	Final	04/2004	7440-46-2
Rad.	Chr.	1 mSv/yr	3	Other	Final	04/2004	7440-46-2

CHLORDANE
Inh.	Int.	0.0002 mg/m3	100	Hepatic	Final	02/2018	12789-03-6
Inh.	Chr.	0.00002 mg/m3	1000	Hepatic	Final	02/2018	12789-03-6
Oral	Acute	0.001 mg/kg/day	1000	Develop.	Final	02/2018	12789-03-6
Oral	Int.	0.0006 mg/kg/day	100	Hepatic	Final	02/2018	12789-03-6
Oral	Chr.	0.0006 mg/kg/day	100	Hepatic	Final	02/2018	12789-03-6

CHLORDECONE
Oral	Acute	0.01 mg/kg/day	100	Neurol.	Final	10/2020	143-50-0
Oral	Int.	3 ug/kg/day	100	Neurol.,Reprod.	Final	10/2020	143-50-0
Oral	Chr.	0.9 ug/kg/day	100	Renal	Final	10/2020	143-50-0

CHLORFENVINPHOS
Oral	Acute	0.002 mg/kg/day	1000	Neurol.	Final	09/1997	470-90-6
Oral	Int.	0.002 mg/kg/day	1000	Immuno.	Final	09/1997	470-90-6
Oral	Chr.	0.0007 mg/kg/day	1000	Neurol.	Final	09/1997	470-90-6

CHLORINE
Inh.	Acute	0.06 ppm	3	Resp.	Final	11/2010	7782-50-5
Inh.	Int.	0.002 ppm	90	Resp.	Final	11/2010	7782-50-5
Inh.	Chr.	0.00005 ppm	30	Resp.	Final	11/2010	7782-50-5

CHLORINE DIOXIDE
Inh.	Int.	0.001 ppm	300	Resp.	Final	09/2004	10049-04-4

CHLORITE
Oral	Int.	0.1 mg/kg/day	30	Develop.	Final	09/2004	7758-19-2

CHLOROBENZENE
Oral	Int.	0.07 mg/kg/day	100	Hepatic	Final	10/2020	108-90-7

CHLOROETHANE
Inh.	Acute	15 ppm	100	Develop.	Final	12/1998	75-00-3

CHLOROFORM
Inh.	Acute	0.1 ppm	30	Hepatic	Final	09/1997	67-66-3
Inh.	Int.	0.05 ppm	300	Hepatic	Final	09/1997	67-66-3
Inh.	Chr.	0.02 ppm	100	Hepatic	Final	09/1997	67-66-3
Oral	Acute	0.3 mg/kg/day	100	Hepatic	Final	09/1997	67-66-3
Oral	Int.	0.1 mg/kg/day	100	Hepatic	Final	09/1997	67-66-3
Oral	Chr.	0.01 mg/kg/day	1000	Hepatic	Final	09/1997	67-66-3

CHLOROMETHANE
Inh.	Acute	0.5 ppm	90	Neurol.	Draft	01/2022	74-87-3
Inh.	Chr.	0.03 ppm	300	Neurol.	Draft	01/2022	74-87-3

CHLORPYRIFOS
Oral	Acute	0.003 mg/kg/day	10	Neurol.	Final	09/1997	2921-88-2
Oral	Int.	0.003 mg/kg/day	10	Neurol.	Final	09/1997	2921-88-2
Oral	Chr.	0.001 mg/kg/day	100	Neurol.	Final	09/1997	2921-88-2

CHROMIUM(III) INSOL. PARTICULATES
Inh.	Int.	0.005 mg/m3	90	Resp.	Final	09/2012	16065-83-1

CHROMIUM(III) SOLUBLE PARTICULATES
Inh.	Int.	0.0001 mg/m3	300	Resp.	Final	09/2012	16065-83-1

CHROMIUM(VI)
Oral	Int.	0.005 mg/kg/day	100	Hemato.	Final	09/2012	18540-29-9
Oral	Chr	0.0009 mg/kg/day	100	Gastro.	Final	09/2012	18540-29-9

CHROMIUM(VI), AEROSOL MISTS
Inh.	Int.	0.000005 mg/m3	100	Resp.	Final	09/2012	18540-29-9
Inh.	Chr.	0.000005 mg/m3	100	Resp.	Final	09/2012	18540-29-9

CHROMIUM(VI), PARTICULATES
Inh.	Int.	0.0003 mg/m3	30	Resp.	Final	09/2012	18540-29-9

COBALT
Inh.	Chr.	0.0001 mg/m3	10	Resp.	Final	04/2004	7440-48-4
Oral	Int.	0.01 mg/kg/day	100	Hemato.	Final	04/2004	7440-48-4
Rad.	Acute	4 mSv	3	Develop.	Final	04/2004	7440-48-4
Rad.	Chr.	1 mSv/yr	3	Other	Final	04/2004	7440-48-4

COPPER
Oral	Acute	0.02 mg/kg/day	3	Gastro.	Draft	04/2022	7440-50-8
Oral	Int.	0.02 mg/kg/day	3	Gastro.	Draft	04/2022	7440-50-8

CRESOLS
Oral	Int.	0.1 mg/kg/day	100	Resp.	Final	09/2008	1319-77-3
Oral	Chr.	0.1 mg/kg/day	1000	Resp.	Final	09/2008	1319-77-3

CYANIDE, SODIUM
Oral	Int.	0.05 mg/kg/day	100	Repro.	Final	07/2006	143-33-9

CYHALOTHRIN
Oral	Acute	0.01 mg/kg/day	100	Gastro.	Final	09/2003	68085-85-8
Oral	Int.	0.01 mg/kg/day	100	Gastro.	Final	09/2003	68085-85-8

CYPERMETHRIN
Oral	Acute	0.02 mg/kg/day	1000	Neurol.	Final	09/2003	52315-07-8

DIBROMOCHLOROMETHANE
Oral	Acute	0.1 mg/kg/day	300	Hepatic	Final	08/2005	124-48-1
Oral	Chr.	0.09 mg/kg/day	300	Hepatic	Final	08/2005	124-48-1

1,1-DICHLOROETHENE
Inh.	Int.	1 ppb	30	Resp.	Final	04/2022	75-35-4
Inh.	Chr.	1 ppb	30	Resp.	Final	04/2022	75-35-4
Oral	Chr.	0.05 mg/kg/day	100	Hepatic	Final	04/2022	75-35-4

1,1-DIMETHYLHYDRAZINE
Inh.	Int.	0.0002 ppm	300	Hepatic	Final	09/1997	57-14-7

1,2-DIBROMO-3-CHLOROPROPANE
Inh.	Int.	0.0002 ppm	100	Repro.	Final	04/2018	96-12-8
Oral	Int.	0.002 mg/kg/day	1000	Repro.	Final	04/2018	96-12-8

1,2-DICHLOROBENZENE
Oral	Acute	0.7 mg/kg/day	100	Hepatic	Final	08/2006	95-50-1
Oral	Int.	0.6 mg/kg/day	100	Hepatic	Final	08/2006	95-50-1
Oral	Chr.	0.3 mg/kg/day	100	Renal	Final	08/2006	95-50-1

1,2-DICHLOROETHANE
Inh.	Acute	0.3 ppm	30	Resp.	Draft	01/2022	107-06-2
Oral	Int.	0.2 mg/kg/day	300	Renal	Draft	01/2022	107-06-2

1,2-DICHLOROETHENE, CIS-
Oral	Acute	1 mg/kg/day	100	Hemato.	Final	08/1996	156-59-2
Oral	Int.	0.3 mg/kg/day	100	Hemato.	Final	08/1996	156-59-2

1,2-DICHLOROETHENE, TRANS-
Inh.	Acute	0.2 ppm	1000	Hepatic	Final	08/1996	156-60-5
Inh.	Int.	0.2 ppm	1000	Hepatic	Final	08/1996	156-60-5
Oral	Int.	0.2 mg/kg/day	100	Hepatic	Final	08/1996	156-60-5

1,2-DICHLOROPROPANE
Inh.	Acute	0.02 ppm	90	Resp.	Final	11/2021	78-87-5
Inh.	Int.	2 ppb	30	Resp.	Final	11/2021	78-87-5
Oral	Acute	0.3 mg/kg/day	100	Hemato.	Final	11/2021	78-87-5
Oral	Int.	0.07 mg/kg/day	1000	Hemato.	Final	11/2021	78-87-5

1,2-DIMETHYLHYDRAZINE
Oral	Int.	0.0008 mg/kg/day	1000	Hepatic	Final	09/1997	540-73-8

1,2-DIPHENYLHYDRAZINE
Oral	Int.	0.05 mg/kg/day	100	Hepatic	Final	10/2020	122-66-7

1,3-DICHLOROBENZENE
Oral	Acute	0.4 mg/kg/day	100	Hepatic	Final	08/2006	541-73-1
Oral	Int.	0.02 mg/kg/day	100	Endocr.	Final	08/2006	541-73-1

1,3-DICHLOROPROPENE
Inh.	Int.	0.008 ppm	30	Resp.	Final	09/2008	542-75-6
Inh.	Chr.	0.007 ppm	30	Resp.	Final	09/2008	542-75-6
Oral	Int.	0.04 mg/kg/day	100	Gastro.	Final	09/2008	542-75-6
Oral	Chr.	0.03 mg/kg/day	100	Gastro.	Final	09/2008	542-75-6

1,3-DINITROBENZENE
Oral	Acute	0.08 mg/kg/day	100	Repro.	Final	06/1995	99-65-0
Oral	Int.	0.0005 mg/kg/day	1000	Hemato.	Final	06/1995	99-65-0

1,4-DICHLOROBENZENE
Inh.	Acute	2 ppm	10	Resp.	Final	08/2006	106-46-7
Inh.	Int.	0.2 ppm	100	Hepatic	Final	08/2006	106-46-7
Inh.	Chr.	0.01 ppm	30	Resp.	Final	08/2006	106-46-7
Oral	Int.	0.07 mg/kg/day	100	Hepatic	Final	08/2006	106-46-7
Oral	Chr.	0.07 mg/kg/day	100	Hepatic	Final	08/2006	106-46-7

1,4-DIOXANE
Inh.	Acute	2 ppm	10	Ocular	Final	04/2012	123-91-1
Inh.	Int.	0.2 ppm	30	Resp.	Final	04/2012	123-91-1
Inh.	Chr.	0.03 ppm	300	Resp.	Final	04/2012	123-91-1
Oral	Acute	5 mg/kg/day	100	Develop.	Final	04/2012	123-91-1
Oral	Int.	0.5 mg/kg/day	100	Hepatic	Final	04/2012	123-91-1
Oral	Chr.	0.1 mg/kg/day	100	Hepatic	Final	04/2012	123-91-1

2,3-DICHLOROPROPENE
Inh.	Acute	0.002 ppm	90	Resp.	Final	09/2008	78-88-6

2,3-DINITROTOLUENE
Oral	Acute	0.09 mg/kg/day	3000	Renal	Final	02/2016	602-01-7

2,4-DICHLOROPHENOL
Oral	Int.	0.02 mg/kg/day	100	Immuno.	Final	06/2022	120-83-2

2,4-DICHLOROPHENOXYACETIC ACID (2,4-D)
Oral	Int.	0.2 mg/kg/day	100	Renal	Final	07/2020	94-75-7
Oral	Chronic	0.2 mg/kg/day	100	Renal	Final	07/2020	94-75-7

2,4-DINITROPHENOL
Oral	Int.	0.07 ug/kg/day	1000	Body Wt.	Final	08/2021	51-28-5

2,4-DINITROTOLUENE
Oral	Acute	0.05 mg/kg/day	100	Neurol.	Final	02/2016	121-14-2
Oral	Int.	0.007 mg/kg/day	100	Hemato.	Final	02/2016	121-14-2
Oral	Chr.	0.001 mg/kg/day	100	Hemato.	Final	02/2016	121-14-2

2,5-DINITROTOLUENE
Oral	Acute	0.007 mg/kg/day	300	Hemato.	Final	02/2016	619-15-8

2,6-DINITROTOLUENE
Oral	Acute	0.09 mg/kg/day	100	Hemato.	Final	02/2016	606-20-2
Oral	Int.	0.004 mg/kg/day	1000	Hemato.	Final	02/2016	606-20-2

3,4-DINITROTOLUENE
Oral	Acute	0.03 mg/kg/day	300	Hemato.	Final	02/2016	610-39-9

3,5-DINITROTOLUENE
Oral	Acute	0.03 mg/kg/day	300	Repro.	Final	02/2016	618-85-9

4,6-DINITRO-O-CRESOL
Oral	Acute	0.004 mg/kg/day	100	Neurol.	Final	01/2018	534-52-1
Oral	Int.	0.004 mg/kg/day	100	Neurol.	Final	01/2018	534-52-1

DDD, P,P'-
Oral	Acute	0.5 ug/kg/day	1000	Develop.	Final	04/2022	72-54-8
Oral	Int.	0.5 ug/kg/day	100	Hepatic	Final	04/2022	72-54-8
Oral	Chr.	0.5 ug/kg/day	100	Hepatic	Final	04/2022	72-54-8

DDE, P,P'-
Oral	Acute	0.5 ug/kg/day	1000	Develop.	Final	04/2022	72-55-9
Oral	Int.	0.5 ug/kg/day	100	Hepatic	Final	04/2022	72-55-9
Oral	Chr.	0.5 ug/kg/day	100	Hepatic	Final	04/2022	72-55-9

DDT, P,P'-
Oral	Acute	0.5 ug/kg/day	1000	Develop.	Final	04/2022	50-29-3
Oral	Int.	0.5 ug/kg/day	100	Hepatic	Final	04/2022	50-29-3
Oral	Chr.	0.5 ug/kg/day	100	Hepatic	Final	04/2022	50-29-3

DEET (N,N-DIETHYL-META-TOLUAMIDE)
Oral	Int.	1 mg/kg/day	100	Develop.	Final	08/2017	134-62-3

DI(2-ETHYLHEXYL)PHTHALATE (DEHP)
Inh.	Int.	0.2 ppb	300	Develop.	Final	01/2022	117-81-7
Oral	Acute	3 ug/kg/day	300	Develop.	Final	01/2022	117-81-7
Oral	Int.	0.1 ug/kg/day	300	Develop.	Final	01/2022	117-81-7

DIAZINON
Inh.	Int.	0.01 mg/m3	30	Neurol.	Final	09/2008	333-41-5
Oral	Acute	0.006 mg/kg/day	100	Neurol.	Final	09/2008	333-41-5
Oral	Int.	0.002 mg/kg/day	100	Neurol.	Final	09/2008	333-41-5
Oral	Chr.	0.0007 mg/kg/day	100	Neurol.	Final	09/2008	333-41-5

DICHLORVOS
Inh.	Acute	0.002 ppm	100	Neurol.	Final	09/1997	62-73-7
Inh.	Int.	0.0003 ppm	100	Neurol.	Final	09/1997	62-73-7
Inh.	Chr.	0.00006 ppm	100	Neurol.	Final	09/1997	62-73-7
Oral	Acute	0.004 mg/kg/day	1000	Neurol.	Final	09/1997	62-73-7
Oral	Int.	0.003 mg/kg/day	10	Neurol.	Final	09/1997	62-73-7
Oral	Chr.	0.0005 mg/kg/day	100	Neurol.	Final	09/1997	62-73-7

DIELDRIN
Oral	Int.	0.1 ug/kg/day	100	Neurol.	Final	06/2022	60-57-1
Oral	Chr.	0.05 ug/kg/day	100	Hepatic	Final	06/2022	60-57-1

DIETHYL PHTHALATE
Oral	Acute	7 mg/kg/day	300	Repro.	Final	06/1995	84-66-2
Oral	Int.	6 mg/kg/day	300	Hepatic	Final	06/1995	84-66-2

DIISOPROPYL METHYLPHOSPHONATE (DIMP)
Oral	Int.	0.8 mg/kg/day	100	Hemato.	Final	08/1998	1445-75-6
Oral	Chr.	0.6 mg/kg/day	100	Hemato.	Final	08/1998	1445-75-6

DIMETHYLARSINIC ACID (DMA)
Oral	Chr.	0.02 mg/kg/day	100	Renal	Final	08/2007	75-60-5

DI-N-BUTYL PHTHALATE
Oral	Acute	0.5 mg/kg/day	100	Develop.	Final	09/2001	84-74-2

DI-N-OCTYL PHTHALATE
Oral	Acute	3 mg/kg/day	300	Hepatic	Final	09/1997	117-84-0
Oral	Int.	0.4 mg/kg/day	100	Hepatic	Final	09/1997	117-84-0

DISULFOTON
Inh.	Acute	0.6 ug/m3	30	Neurol.	Final	08/2022	298-04-4
Inh.	Int.	0.6 ug/m3	30	Neurol.	Final	08/2022	298-04-4
Oral	Acute	0.3 ug/kg/day	100	Neurol.	Final	08/2022	298-04-4
Oral	Int.	0.09 ug/kg/day	100	Neurol., Develop.	Final	08/2022	298-04-4
Oral	Chr.	0.06 ug/kg/day	1000	Neurol.	Final	08/2022	298-04-4

ENDOSULFAN
Oral	Acute	0.007 mg/kg/day	100	Neurol.	Final	08/2015	115-29-7
Oral	Int.	0.005 mg/kg/day	100	Immuno.	Final	08/2015	115-29-7
Oral	Chr.	0.005 mg/kg/day	100	Immuno.	Final	08/2015	115-29-7

ENDRIN
Oral	Acute	0.6 ug/kg/day	100	Neurol.	Final	03/2021	72-20-8
Oral	Int.	0.6 ug/kg/day	100	Neurol.	Final	03/2021	72-20-8
Oral	Chr.	0.3 ug/kg/day	100	Neurol.,Hepatic	Final	03/2021	72-20-8

ETHION
Oral	Acute	0.002 mg/kg/day	30	Neurol.	Final	09/2000	563-12-2
Oral	Int.	0.002 mg/kg/day	30	Neurol.	Final	09/2000	563-12-2
Oral	Chr.	0.0004 mg/kg/day	150	Neurol.	Final	09/2000	563-12-2

ETHYLBENZENE
Inh.	Acute	5 ppm	30	Neurol.	Final	11/2010	100-41-4
Inh.	Int.	2 ppm	30	Neurol.	Final	11/2010	100-41-4
Inh.	Chr.	0.06 ppm	300	Renal	Final	11/2010	100-41-4
Oral	Int.	0.4 mg/kg/day	30	Hepatic	Final	11/2010	100-41-4

ETHYLENE GLYCOL
Inh.	Acute	2 mg/m3	10	Renal	Final	11/2010	107-21-1
Oral	Acute	0.8 mg/kg/day	100	Develop.	Final	11/2010	107-21-1
Oral	Int.	0.8 mg/kg/day	100	Develop.	Final	11/2010	107-21-1

ETHYLENE OXIDE
Inh.	Acute	0.4 ppm	30	Develop.	Final	08/2022	75-21-8
Inh.	Int.	0.07 ppm	30	Develop.	Final	08/2022	75-21-8

FLUORANTHENE
Oral	Int.	0.4 mg/kg/day	300	Hepatic	Final	08/1995	206-44-0

FLUORENE
Oral	Int.	0.4 mg/kg/day	300	Hepatic	Final	08/1995	86-73-7

FLUORIDE, SODIUM
Oral	Chr.	0.05 mg/kg/day	3	Musculo.	Final	09/2003	7681-49-4

FLUORINE
Inh.	Acute	0.01 ppm	10	Resp.	Final	09/2003	7782-41-4

FORMALDEHYDE
Inh.	Acute	0.04 ppm	9	Resp.	Final	07/1999	50-00-0
Inh.	Int.	0.03 ppm	30	Resp.	Final	07/1999	50-00-0
Inh.	Chr.	0.008 ppm	30	Resp.	Final	07/1999	50-00-0
Oral	Int.	0.3 mg/kg/day	100	Gastro.	Final	07/1999	50-00-0
Oral	Chr.	0.2 mg/kg/day	100	Gastro.	Final	07/1999	50-00-0

FUEL OIL NO.2
Inh.	Acute	0.02 mg/m3	1000	Neurol.	Final	06/1995	68476-30-2

GLUTARALDEHYDE
Inh.	Acute	0.001 ppm	3	Resp.	Final	07/2017	111-30-8
Inh.	Int.	0.00003 ppm	3	Resp.	Final	07/2017	111-30-8
Oral	Chr.	0.1 mg/kg/day	30	Gastro.	Final	07/2017	111-30-8

GLYPHOSATE TECHNICAL
Oral	Acute	1 mg/kg/day	100	Gastro.	Final	08/2020	1071-83-6
Oral	Int.	1 mg/kg/day	100	Gastro.	Final	08/2020	1071-83-6
Oral	Chr.	1 mg/kg/day	100	Gastro.	Final	08/2020	1071-83-6

GUTHION (AZINPHOS-METHYL)
Inh.	Acute	0.02 mg/m3	30	Neurol.	Final	09/2008	86-50-0
Inh.	Int.	0.01 mg/m3	30	Neurol.	Final	09/2008	86-50-0
Inh.	Chr.	0.01 mg/m3	30	Neurol.	Final	09/2008	86-50-0
Oral	Acute	0.01 mg/kg/day	100	Neurol.	Final	09/2008	86-50-0
Oral	Int.	0.003 mg/kg/day	100	Neurol.	Final	09/2008	86-50-0
Oral	Chr.	0.003 mg/kg/day	100	Neurol.	Final	09/2008	86-50-0

1,2,3,6,7,8-HEXACHLORODIBENZOFURAN
Oral	Int.	5 ng/kg/day	100	Hepatic, Endocrine	Draft	01/2022	57117-44-9

2-HEXANONE
Oral	Chr.	0.05 mg/kg/day	3000	Neurol.	Final	02/2020	591-78-6

HEPTACHLOR
Oral	Acute	0.0006 mg/kg/day	3000	Repro.	Final	08/2007	76-44-8
Oral	Int.	0.0001 mg/kg/day	300	Immuno.	Final	08/2007	76-44-8

HEXACHLOROBENZENE
Oral	Acute	0.008 mg/kg/day	300	Develop.	Final	08/2015	118-74-1
Oral	Int.	0.0001 mg/kg/day	90	Repro.	Final	08/2015	118-74-1
Oral	Chr.	0.00007 mg/kg/day	300	Hepatic	Final	08/2015	118-74-1

HEXACHLOROBUTADIENE
Oral	Acute	6 ug/kg/day	1000	Renal	Final	03/2021	87-68-3
Oral	Int.	2 ug/kg/day	100	Renal	Final	03/2021	87-68-3

HEXACHLOROCYCLOHEXANE, ALPHA-
Oral	Chr.	0.008 mg/kg/day	100	Hepatic	Final	08/2005	319-84-6

HEXACHLOROCYCLOHEXANE, BETA-
Oral	Acute	0.05 mg/kg/day	100	Neurol.	Final	08/2005	319-85-7
Oral	Int.	0.0006 mg/kg/day	300	Hepatic	Final	08/2005	319-85-7

HEXACHLOROCYCLOHEXANE, GAMMA-
Oral	Acute	0.003 mg/kg/day	300	Reprod.	Final	08/2005	58-89-9
Oral	Int.	0.00001 mg/kg/day	1000	Immuno.	Final	08/2005	58-89-9

HEXACHLOROCYCLOPENTADIENE
Inh.	Int.	0.01 ppm	30	Resp.	Final	07/1999	77-47-4
Inh.	Chr.	0.0002 ppm	90	Resp.	Final	07/1999	77-47-4
Oral	Int.	0.1 mg/kg/day	100	Renal	Final	07/1999	77-47-4

HEXACHLOROETHANE
Inh.	Acute	6 ppm	30	Neurol.	Final	09/1997	67-72-1
Inh.	Int.	6 ppm	30	Neurol.	Final	09/1997	67-72-1
Oral	Acute	1 mg/kg/day	100	Hepatic	Final	09/1997	67-72-1
Oral	Int.	0.01 mg/kg/day	100	Hepatic	Final	09/1997	67-72-1

HEXAMETHYLENE DIISOCYANATE
Inh.	Int.	0.00003 ppm	30	Resp.	Final	08/1998	822-06-0
Inh.	Chr.	0.00001 ppm	90	Resp.	Final	08/1998	822-06-0

HEXANE, N-
Inh.	Chr.	0.6 ppm	100	Neurol.	Final	07/1999	110-54-3

HMX (CYCLOTETRAMETHYLENE TETRANITRAMINE)
Oral	Acute	0.1 mg/kg/day	1000	Neurol.	Final	09/1997	2691-41-0
Oral	Int.	0.05 mg/kg/day	1000	Hepatic	Final	09/1997	2691-41-0

HYDRAZINE
Inh.	Int.	0.004 ppm	300	Hepatic	Final	09/1997	302-01-2

HYDROGEN FLUORIDE
Inh.	Acute	0.02 ppm	30	Resp.	Final	09/2003	7664-39-3

HYDROGEN SULFIDE
Inh.	Acute	0.07 ppm	27	Resp.	Final	11/2016	7783-06-4
Inh.	Int.	0.02 ppm	30	Resp.	Final	11/2016	7783-06-4

IODIDE
Oral	Acute	0.01 mg/kg/day	1	Endocr.	Final	04/2004	7553-56-2
Oral	Chr.	0.01 mg/kg/day	1	Endocr.	Final	04/2004	7553-56-2

IONIZING RADIATION, N.O.S.
Rad.	Acute	4 mSv	3	Neurol.	Final	09/1999	HZ1800-45-T
Rad.	Chr.	1 mSv/yr	3	Other	Final	09/1999	HZ1800-45-T

ISOPHORONE
Oral	Int.	3 mg/kg/day	100	Other	Final	07/2018	78-59-1
Oral	Chr.	0.2 mg/kg/day	1000	Hepatic	Final	07/2018	78-59-1

JP-4
Inh.	Int.	9 mg/m3	300	Hepatic	Final	06/1995	50815-00-4

JP-5
Inh.	Int.	2 mg/m<sup>3</sup>	90	Hepatic	Final	03/2017	8008-20-6

JP-7
Inh.	Chr.	0.3 mg/m3	300	Hepatic	Final	06/1995	HZ0600-22-T

JP-8
Inh.	Int.	3 mg/m<sup>3</sup>	30	Neurol.	Final	03/2017	8008-20-6
Oral	Acute	3 mg/kg/day	100	Immuno.	Final	03/2017	8008-20-6
Oral	Int.	0.3 mg/kg/day	1000	Develop.	Final	03/2017	8008-20-6

KEROSENE
Inh.	Int.	0.01 mg/m3	1000	Hepatic	Final	06/1995	8008-20-6

1-METHYLNAPHTHALENE
Oral	Chr.	0.07 mg/kg/day	1000	Resp.	Final	08/2005	90-12-0

2-METHYLNAPHTHALENE
Oral	Chr.	0.04 mg/kg/day	100	Resp.	Final	08/2005	91-57-6

4,4'-METHYLENEBIS(2-CHLOROANILINE) (MBOCA)
Oral	Chr.	0.003 mg/kg/day	3000	Hepatic	Final	10/2017	101-14-4

4,4'-METHYLENEDIANILINE
Oral	Acute	0.2 mg/kg/day	150	Hepatic	Final	08/1998	101-77-9
Oral	Int.	0.08 mg/kg/day	100	Hepatic	Final	08/1998	101-77-9

MALATHION
Inh.	Acute	0.2 mg/m3	100	Neurol.	Final	09/2003	121-75-5
Inh.	Int.	0.02 mg/m3	1000	Resp.	Final	09/2003	121-75-5
Oral	Int.	0.02 mg/kg/day	10	Neurol.	Final	09/2003	121-75-5
Oral	Chr.	0.02 mg/kg/day	100	Neurol.	Final	09/2003	121-75-5

MANGANESE, RESPIRABLE
Inh.	Chr.	0.3 ug/m3	100	Neurol.	Final	09/2012	7439-96-5

MERCURY
Inh.	Chr.	0.3 ug/m3	10	Neurol.	Draft	04/2022	7439-97-6

MERCURY, INORGANIC SALTS (MERCURIC CHLORIDE, ETC.)
Oral	Acute	2 ug/kg/day	100	Renal	Draft	04/2022	7487-94-7
Oral	Int.	0.01 ug/kg/day	1000	Renal	Draft	04/2022	7487-94-7

METHOXYCHLOR
Oral	Int.	0.005 mg/kg/day	1000	Repro.	Final	09/2002	72-43-5

METHYL PARATHION
Oral	Int.	0.0007 mg/kg/day	300	Neurol.	Final	09/2001	298-00-0
Oral	Chr.	0.0003 mg/kg/day	100	Hemato.	Final	09/2001	298-00-0

METHYL tert-BUTYL ETHER (MTBE)
Inh.	Acute	2 ppm	30	Neurol.	Draft	01/2022	1634-04-4
Inh.	Int.	1 ppm	30	Neurol.,Hepatic	Draft	01/2022	1634-04-4
Inh.	Chr.	1 ppm	30	Renal	Draft	01/2022	1634-04-4
Oral	Int.	0.6 mg/kg/day	100	Neurol.	Draft	01/2022	1634-04-4

METHYLENE CHLORIDE
Inh.	Acute	0.6 ppm	100	Neurol.	Final	09/2000	75-09-2
Inh.	Int.	0.3 ppm	90	Hepatic	Final	09/2000	75-09-2
Inh.	Chr.	0.3 ppm	30	Hepatic	Final	09/2000	75-09-2
Oral	Acute	0.2 mg/kg/day	100	Neurol.	Final	09/2000	75-09-2
Oral	Chr.	0.06 mg/kg/day	100	Hepatic	Final	09/2000	75-09-2

METHYLENEDIPHENYL DIISOCYANATE (MDI), POLYMERIC
Inh.	Chr.	0.001 mg/m3	30	Resp.	Final	06/2018	9016-87-9

METHYLMERCURY
Oral	Chr.	0.1 ug/kg/day	3	Develop.	Draft	04/2022	22967-92-6

MIREX
Oral	Chr.	0.3 ug/kg/day	300	Hepatic	Final	10/2020	2385-85-5

MOLYBDENUM
Inh.	Chr.	2 ug/m3	30	Resp.	Final	05/2020	1313-27-5
Oral	Int.	0.06 mg/kg/day	300	Renal	Final	05/2020	7439-98-7

MONOMETHYLARSONIC ACID (MMA)
Oral	Int.	0.1 mg/kg/day	100	Gastro.	Final	08/2007	124-58-3
Oral	Chr.	0.01 mg/kg/day	100	Renal	Final	08/2007	124-58-3

NAPHTHALENE
Inh.	Chr.	0.0007 ppm	300	Resp.	Final	08/2005	91-20-3
Oral	Acute	0.6 mg/kg/day	90	Neurol.	Final	08/2005	91-20-3
Oral	Int.	0.6 mg/kg/day	90	Neurol.	Final	08/2005	91-20-3

NICKEL
Inh.	Int.	0.0002 mg/m3	30	Resp.	Final	08/2005	7440-02-0
Inh.	Chr.	0.00009 mg/m3	30	Resp.	Final	08/2005	7440-02-0

NITRATE
Oral	Acute	4 mg/kg/day	1	Hemato.	Final	07/2017	14797-55-8
Oral	Int.	4 mg/kg/day	1	Hemato.	Final	07/2017	14797-55-8
Oral	Chr.	4 mg/kg/day	1	Hemato.	Final	07/2017	14797-55-8

NITRITE
Oral	Acute	0.1 mg/kg/day	2	Hemato.	Final	07/2017	14797-65-0
Oral	Int.	0.1 mg/kg/day	2	Hemato.	Final	07/2017	14797-65-0
Oral	Chr.	0.1 mg/kg/day	2	Hemato.	Final	07/2017	14797-65-0

NITROBENZENE
Inh.	Acute	0.04 ppm	90	Hemato.	Draft	04/2022	98-95-3
Inh.	Int.	3 ppb	300	Hemato.	Draft	04/2022	98-95-3
Inh.	Chr.	1 ppb	30	Resp.	Draft	04/2022	98-95-3
Oral	Acute	0.05 mg/kg/day	100	Hemato.	Draft	04/2022	98-95-3
Oral	Int.	0.02 mg/kg/day	100	Hemato.	Draft	04/2022	98-95-3

N-NITROSODIMETHYLAMINE (NDMA)
Oral	Acute	0.01 ug/kg/day	100	Hemato.	Draft	01/2022	62-75-9

1,2,3,7,8-PENTACHLORODIBENZOFURAN
Oral	Int.	7 ng/kg/day	100	Hepatic	Draft	01/2022	57117-41-6

2,3,4,7,8-PENTACHLORODIBENZOFURAN
Oral	Acute	0.5 ng/kg/day	1000	Develop.	Draft	01/2022	57117-31-4
Oral	Int.	7 pg/kg/day	100	Endocrine	Draft	01/2022	57117-31-4
Oral	Chr.	4 pg/kg/day	1000	Hepatic, Endocrine	Draft	01/2022	57117-31-4

PARATHION
Inh.	Int.	20 ng/m3	100	Neurol.	Final	01/2017	56-38-2
Oral	Int.	0.009 mg/kg/day	10	Neurol.	Final	01/2017	56-38-2

PBDE, DECABROMINATED
Oral	Acute	0.01 mg/kg/day	100	Develop.	Final	03/2017	67774-32-7
Oral	Int.	0.0002 mg/kg/day	300	Endocr.	Final	03/2017	67774-32-7

PENTACHLOROPHENOL
Oral	Acute	5 ug/kg/day	1000	Develop.	Final	04/2022	87-86-5
Oral	Chr.	5 ug/kg/day	300	Hepatic	Final	04/2022	87-86-5

PERCHLORATES
Oral	Chr.	0.0007 mg/kg/day	10	Endocr.	Final	09/2008	14797-73-0

PERFLUOROHEXANE SULFONIC ACID (PFHxS)
Oral	Int.	0.02 ug/kg/day	300	Endocr.	Final	03/2020	355-46-4

PERFLUORONONANOIC ACID (PFNA)
Oral	Int.	3 ng/kg/day	300	Develop.	Final	03/2020	375-95-1

PERFLUOROOCTANE SULFONIC ACID (PFOS)
Oral	Int.	2 ng/kg/day	300	Develop.	Final	03/2020	1763-23-1

PERFLUOROOCTANOIC ACID (PFOA)
Oral	Int.	3 ng/kg/day	300	Develop.	Final	03/2020	335-67-1

PERMETHRIN
Oral	Acute	0.3 mg/kg/day	100	Neurol.	Final	09/2003	52645-53-1
Oral	Int.	0.2 mg/kg/day	100	Neurol.	Final	09/2003	52645-53-1

PHENOL
Oral	Acute	1 mg/kg/day	100	Body Wt.	Final	09/2008	108-95-2

PHOSPHORUS, WHITE
Inh.	Acute	0.02 mg/m3	30	Resp.	Final	09/1997	7723-14-0
Oral	Int.	0.0002 mg/kg/day	100	Repro.	Final	09/1997	7723-14-0

POLYBROMINATED BIPHENYLS (PBBS)
Oral	Acute	0.01 mg/kg/day	100	Endocr.	Final	09/2004	36355-01-8

POLYBROMINATED DIPHENYL ETHERS (PBDES), LOWER BROMINATED
Inh.	Int.	0.006 mg/m3	90	Endocr.	Final	03/2017	32536-52-0
Oral	Acute	0.00006 mg/kg/day	1000	Develop.	Final	03/2017	60348-60-9
Oral	Int.	0.000003 mg/kg/day	300	Reprod.	Final	03/2017	5436-43-1

POLYCHLORINATED BIPHENYLS (PCBs) (Aroclor 1254)
Oral	Int.	0.03 ug/kg/day	300	Neurol.	Final	11/2000	11097-69-1
Oral	Chr.	0.02 ug/kg/day	300	Immuno.	Final	11/2000	11097-69-1

PROPYLENE GLYCOL
Inh.	Int.	0.009 ppm	1000	Resp.	Final	09/1997	57-55-6

PROPYLENE GLYCOL DINITRATE
Inh.	Acute	0.003 ppm	10	Neurol.	Final	06/1995	6423-43-4
Inh.	Int.	0.00004 ppm	1000	Hemato.	Final	06/1995	6423-43-4
Inh.	Chr.	0.00004 ppm	1000	Hemato.	Final	06/1995	6423-43-4

RDX (CYCLONITE)
Oral	Acute	0.2 mg/kg/day	30	Neurol.	Final	01/2012	121-82-4
Oral	Int.	0.1 mg/kg/day	30	Neurol.	Final	01/2012	121-82-4
Oral	Chr.	0.1 mg/kg/day	30	Neurol.	Final	01/2012	121-82-4

REFRACTORY CERAMIC FIBERS
Inh.	Chr.	0.03 fibers/cc	30	Resp.	Final	09/2004	HZ0900-26-T

S,S,S-TRIBUTYL PHOSPHOROTRITHIOATE (TRIBUFOS)
Inh.	Int.	0.04 mg/m3	30	Neurol.	Final	03/2020	78-48-8
Oral	Int.	0.003 mg/kg/day	100	Neurol.	Final	03/2020	78-48-8
Oral	Chr.	0.5 ug/kg/day	100	Gastro.	Final	03/2020	78-48-8

SELENIUM
Oral	Chr.	0.005 mg/kg/day	3	Dermal	Final	09/2003	7782-49-2

STRONTIUM
Oral	Int.	2 mg/kg/day	90	Musculo.	Final	04/2004	7440-24-6

STYRENE
Inh.	Acute	5 ppm	10	Neurol.	Final	11/2010	100-42-5
Inh.	Chr.	0.2 ppm	30	Neurol.	Final	11/2010	100-42-5
Oral	Acute	0.1 mg/kg/day	1000	Neurol.	Final	11/2010	100-42-5

SULFUR DIOXIDE
Inh.	Acute	0.01 ppm	9	Resp.	Final	12/1998	7446-09-5

SULFUR MUSTARD
Inh.	Acute	0.0007 mg/m3	30	Ocular	Final	09/2003	505-60-2
Inh.	Int.	0.00002 mg/m3	30	Ocular	Final	09/2003	505-60-2
Oral	Acute	0.5 µg/kg/day	1000	Develop.	Final	09/2003	505-60-2
Oral	Int.	0.07 µg/kg/day	300	Gastro.	Final	09/2003	505-60-2

1,1,1-TRICHLOROETHANE
Inh.	Acute	2 ppm	100	Neurol.	Final	07/2006	71-55-6
Inh.	Int.	0.7 ppm	100	Neurol.	Final	07/2006	71-55-6
Oral	Int.	20 mg/kg/day	100	Body Wt.	Final	07/2006	71-55-6

1,1,2,2-TETRACHLOROETHANE
Oral	Int.	0.5 mg/kg/day	100	Hepatic	Final	09/2008	79-34-5

1,1,2-TRICHLOROETHANE
Inh.	Acute	0.03 ppm	270	Resp.	Final	03/2021	79-00-5
Inh.	Int.	2 ppb	30	Resp.	Final	03/2021	79-00-5
Oral	Acute	0.5 mg/kg/day	100	Hepatic	Final	03/2021	79-00-5
Oral	Int.	0.04 mg/kg/day	100	Immuno.	Final	03/2021	79-00-5

1,2,3-TRICHLOROPROPANE
Inh.	Acute	1 ppb	30	Resp.	Final	08/2021	96-18-4
Oral	Int.	0.03 mg/kg/day	100	Hemato.	Final	08/2021	96-18-4
Oral	Chr.	0.01 mg/kg/day	100	Hepatic	Final	08/2021	96-18-4

1,2,4 - TRICHLOROBENZENE
Oral	Int.	0.1 mg/kg/day	100	Hepatic	Final	10/2014	120-82-1
Oral	Chr.	0.1 mg/kg/day	100	Hepatic	Final	10/2014	120-82-1

2,3,4,6-TETRACHLOROPHENOL
Oral	Acute	0.08 mg/kg/day	100	Hepatic	Final	06/2022	58-90-2
Oral	Int.	0.01 mg/kg/day	100	Hepatic	Final	06/2022	58-90-2

2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN
Oral	Acute	0.0002 ug/kg/day	21	Immuno.	Final	12/1998	1746-01-6
Oral	Int.	0.00002 ug/kg/day	30	Lymphor.	Final	12/1998	1746-01-6
Oral	Chr.	0.000001 ug/kg/day	90	Develop.	Final	12/1998	1746-01-6

2,4,5-TRICHLOROPHENOL
Oral	Int.	1 mg/kg/day	100	Hepatic,Renal	Final	06/2022	95-95-4

2,4,6-TRICHLOROPHENOL
Oral	Int.	5 ug/kg/day	100	Hepatic	Final	06/2022	88-06-2

2,4,6-TRINITROTOLUENE
Oral	Int.	0.0005 mg/kg/day	1000	Hepatic	Final	06/1995	118-96-7

TETRACHLOROETHYLENE
Inh.	Acute	0.006 ppm	300	Neurol.	Final	06/2019	127-18-4
Inh.	Int.	0.006 ppm	300	Neurol.	Final	06/2019	127-18-4
Inh.	Chr.	0.006 ppm	300	Neurol.	Final	06/2019	127-18-4
Oral	Acute	0.008 mg/kg/day	300	Neurol.	Final	06/2019	127-18-4
Oral	Int.	0.008 mg/kg/day	300	Neurol.	Final	06/2019	127-18-4
Oral	Chr.	0.008 mg/kg/day	300	Neurol.	Final	06/2019	127-18-4

TIN, DIBUTYL-, DICHLORIDE
Oral	Int.	0.005 mg/kg/day	1000	Immuno.	Final	08/2005	683-18-1

TIN, INORGANIC
Oral	Int.	0.3 mg/kg/day	100	Hemato.	Final	08/2005	7440-31-5

TIN, TRIBUTYL-, OXIDE
Oral	Int.	0.0003 mg/kg/day	100	Immuno.	Final	08/2005	56-35-9
Oral	Chr.	0.0003 mg/kg/day	100	Immuno.	Final	08/2005	56-36-9

TITANIUM TETRACHLORIDE
Inh.	Int.	0.01 mg/m3	90	Resp.	Final	09/1997	7550-45-0
Inh.	Chr.	0.0001 mg/m3	90	Resp.	Final	09/1997	7550-45-0

TOLUENE
Inh.	Acute	2 ppm	9	Neurol.	Final	06/2017	108-88-3
Inh.	Chr.	1 ppm	10	Neurol.	Final	06/2017	108-88-3
Oral	Acute	0.8 mg/kg/day	300	Neurol.	Final	06/2017	108-88-3
Oral	Int.	0.2 mg/kg/day	100	Immuno.	Final	06/2017	108-88-3

TOLUENE DIISOCYANATE (TDI)
Inh.	Acute	0.00001 ppm	100	Resp.	Final	06/2018	26471-62-5
Inh.	Chr.	0.000003 ppm	100	Resp.	Final	06/2020	26471-62-5

TOXAPHENE
Oral	Acute	0.05 mg/kg/day	100	Neurol.	Final	10/2014	8001-35-2
Oral	Int.	0.002 mg/kg/day	100	Immuno.	Final	10/2014	8001-35-2

TRIBUTYL PHOSPHATE (TNBP)
Oral	Acute	1.1 mg/kg/day	100	Body Wt.	Final	09/2012	126-73-8
Oral	Int.	0.08 mg/kg/day	100	Renal	Final	09/2012	126-73-8
Oral	Chr.	0.08 mg/kg/day	100	Renal	Final	09/2012	126-73-8

TRICHLOROETHYLENE
Inh.	Int.	0.0004 ppm	10	Develop.	Final	06/2019	79-01-6
			100	Immuno.
Inh.	Chr.	0.0004 ppm	10	Develop.	Final	06/2019	79-01-6
			100	Immuno.
Oral	Int.	0.0005 mg/kg/day	10	Develop.	Final	06/2019	79-01-6
			100	Immuno.
			1000	Immuno.
Oral	Chr.	0.0005 mg/kg/day	10	Develop.	Final	06/2019	79-01-6
			100	Immuno.
			1000	Immuno.

TRICRESYL PHOSPHATE (TCP)
Oral	Int.	0.04 mg/kg/day	100	Reprod.	Final	09/2012	1330-78-5
Oral	Chr.	0.02 mg/kg/day	100	Reprod.	Final	09/2012	1330-78-5

TRIS(1,3-DICHLORO-2-PROPYL) PHOSPHATE (TDCP)
Oral	Int.	0.05 mg/kg/day	100	Renal	Final	09/2012	13674-87-8
Oral	Chr.	0.02 mg/kg/day	100	Renal	Final	09/2012	13674-87-8

TRIS(2-BUTOXYETHYL) PHOSPHATE (TBEP)
Oral	Acute	4.8 mg/kg/day	100	Body Wt.	Final	09/2012	78-51-3
Oral	Int.	0.09 mg/kg/day	100	Hepatic	Final	09/2012	78-51-3

TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP)
Oral	Int.	0.6 mg/kg/day	100	Neurol.	Final	09/2012	115-96-8
Oral	Chr.	0.2 mg/kg/day	100	Renal	Final	09/2012	115-96-8

URANIUM, INSOLUBLE COMPOUNDS
Inh.	Int.	0.002 mg/m3	100	Renal	Final	02/2013	7440-61-1
Inh.	Chr.	0.0008 mg/m3	1000	Resp.	Final	02/2013	7440-61-1

URANIUM, SOLUBLE SALTS
Inh.	Int.	0.0001 mg/m3	300	Renal	Final	02/2013	7440-61-1
Inh.	Chr.	0.00004 mg/m3	100	Renal	Final	02/2013	7440-61-1
Oral	Acute	0.002 mg/kg/day	100	Develop.	Final	02/2013	7440-61-1
Oral	Int.	0.0002 mg/kg/day	300	Renal	Final	02/2013	7440-61-1

VANADIUM
Inh.	Acute	0.0008 mg/m3	90	Resp.	Final	09/2012	7440-62-2
Inh.	Chr.	0.0001 mg/m3	30	Resp.	Final	09/2012	7440-62-2
Oral	Int.	0.01 mg/kg/day	10	Hemato.	Final	09/2012	7440-62-2

VINYL ACETATE
Inh.	Int.	0.01 ppm	100	Resp.	Final	07/1992	108-05-4

VINYL CHLORIDE
Inh.	Acute	0.5 ppm	30	Develop.	Final	07/2006	75-01-4
Inh.	Int.	0.03 ppm	30	Hepatic	Final	07/2006	75-01-4
Oral	Chr.	0.003 mg/kg/day	30	Hepatic	Final	07/2006	75-01-4

XYLENES, MIXED
Inh.	Acute	2 ppm	30	Neurol.	Final	08/2007	1330-20-7
Inh.	Int.	0.6 ppm	90	Neurol.	Final	08/2007	1330-20-7
Inh.	Chr.	0.05 ppm	300	Neurol.	Final	08/2007	1330-20-7
Oral	Acute	1 mg/kg/day	100	Neurol.	Final	08/2007	1330-20-7
Oral	Int.	0.4 mg/kg/day	1000	Neurol.	Final	08/2007	1330-20-7
Oral	Chr.	0.2 mg/kg/day	1000	Neurol.	Final	08/2007	1330-20-7

ZINC
Oral	Int.	0.3 mg/kg/day	3	Hemato.	Final	08/2005	7440-66-6
Oral	Chr.	0.3 mg/kg/day	3	Hemato.	Final	08/2005	7440-66-6

* Total Factors: Final value of all uncertainty and modifying factors, multiplied together.

Total number of MRLs: 475

165 Inhalation, 302 Oral, and 8 External Radiation MRLs

For Duration, Acute = 1 to 14 days, Intermediate = 15 to 364 days, and Chronic = 1 year or longer.

For general information on ATSDR Minimal Risk Levels, see www.atsdr.cdc.gov/MRLs.

For more information on a specific MRL, please refer to our Toxicological Profiles,
particularly Appendix A of Profiles released after 1995.
The Toxicological Profiles can be found online at www.atsdr.cdc.gov/ToxProfiles.

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Page last reviewed: August 15, 2022

Content source: Agency for Toxic Substances and Disease Registry