Hexamethylene Diisocyanate (HDI)

CAS ID#: 822-06-0

Affected Organ Systems: Immunological (Immune System), Respiratory (From the Nose to the Lungs)

Cancer Classification:  Please contact NTP, IARC, or EPA with questions on cancer and cancer classification.

Chemical Classification: None

Summary: Hexamethylene diisocyanate is a pale yellow liquid with a strong odor. It is an industrial chemical that is not known to occur naturally. It is also commonly known as HDI, 1,6-hexamethylene diisocyanate, 1,6-diisocyanatohexane, Mondur HX, and Desmodur H. Hexamethylene diisocyanate is mainly used to make polyurethane foams and coatings. It is also used as a hardener in automobile and airplane paints.

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Public Health Statement - Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile.

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Toxicological Profile - Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance.

Minimal Risk Levels (MRL) - The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure.

Page last reviewed: February 10, 2021