Toxicological Profile for Nickel

CAS#: 7440-02-0

Toxicological Profile Information

The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.

The focus of the profile is on health and toxicologic information. Therefore, each profile begins with a Public Health Statement that summarizes in nontechnical language, a substance's relevant properties.

A useful two page information sheet, the ToxFAQs™, is also available.

Toxicological Profile Access

In order to access the ATSDR toxicological profile PDF files below, you must have Adobe Acrobat Reader. You may download that program free from Adobe.

Complete Profile pdf icon[PDF - 3.8 MB]

Preface pdf icon[PDF - 573.2 KB]

1. Public Health Statement pdf icon[PDF - 701.2 KB]

2. Relevance to Public Health pdf icon[PDF - 870.2 KB]

3. Health Effects pdf icon[PDF - 4.0 MB]

4. Chemical and Physical Information pdf icon[PDF - 868.9 KB]

5. Production, Import, Use, and Disposal pdf icon[PDF - 726.1 KB]

6. Potential for Human Exposure pdf icon[PDF - 1.2 MB]

7. Analytical Methods pdf icon[PDF - 746.3 KB]

8. Regulations and Advisories pdf icon[PDF - 780.9 KB]

9. References pdf icon[PDF - 1 MB]

10. Glossary pdf icon[PDF - 701.5 KB]

Appendices pdf icon[PDF - 840.2 KB]


Agency for Toxic Substances and Disease Registry (ATSDR). 2005. Toxicological profile for Nickel. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.


All ATSDR toxicological profile PDF files are electronic conversions from other electronic text files. This conversion may have resulted in character translation or format errors.

Regulations or guidelines may change. Please check with the appropriate agency for any changes to the regulations or guidelines cited.

Where can I get more information?

If you have questions or concerns, please contact your community or state health or environmental quality department or:

For more information, contact:
Agency for Toxic Substances and Disease Registry
Division of Toxicology and Human Health Sciences
4770 Buford Highway
Chamblee, GA 30341-3717
Phone: 1-800-CDC-INFO 888-232-6348 (TTY)
Email: Contact CDC-INFO

ATSDR can also tell you the location of occupational and environmental health clinics. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances.

Page last reviewed: March 25, 2014