Toxicological Profile for Hexamethylene Diisocyanate (HDI)
Toxicological Profile Information
The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.
The focus of the profile is on health and toxicologic information.
Therefore, each profile begins with a Public Health Statement that summarizes in nontechnical
language, a substance's relevant properties.
A useful two page information sheet, the ToxFAQsTM, is also available.
Toxicological Profile Access
In order to access the ATSDR toxicological profile PDF files below, you must have Adobe Acrobat Reader. You may download that program free from Adobe.
Complete Profilepdf icon[PDF - 4.0 MB]
Prefacepdf icon[PDF - 562 KB]
1. Public Health Statementpdf icon[PDF - 142 KB]
2. Health Effectspdf icon[PDF - 1.84 MB]
3. Chemical and Physical Informationpdf icon[PDF - 371 KB]
4. Production, Import, Use, and Disposalpdf icon[PDF - 49.9 KB]
5. Potential for Human Exposurepdf icon[PDF - 310 KB]
6. Analytical Methodspdf icon[PDF - 243 KB]
7. Regulations and Advisoriespdf icon[PDF - 137 KB]
8. Referencespdf icon[PDF - 92.8 KB]
9. Glossarypdf icon[PDF - 54.9 KB]
Appendicespdf icon[PDF - 901 KB]
Agency for Toxic Substances and Disease
Registry (ATSDR). 1998. Toxicological profile for hexamethylene
diisocyanate (HDI). Atlanta, GA: U.S. Department of Health
and Human Services, Public Health Service.
All ATSDR toxicological profile PDF files are electronic conversions from other electronic text files. This conversion may have resulted in character translation or format errors.
Regulations or guidelines may change. Please check with the appropriate agency for any changes to the regulations or guidelines cited.
Where can I get more information?
If you have questions or concerns, please contact your community or state health or environmental quality department or:
For more information, contact:
Agency for Toxic Substances and Disease Registry
Office of Innovation and Analytics, Toxicology Section
4770 Buford Highway
Chamblee, GA 30341-3717
Phone: 1-800-CDC-INFO 888-232-6348 (TTY)
Email: Contact CDC-INFO
ATSDR can also tell you the location of occupational and environmental health clinics. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances.