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Virus Name/Prototype
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  Kumlinge   KUMV

Arbovirus

No

4

Placed in Level 4 based on the close antigenic relationship with a known Level 4 agent, Russian spring-summer encephalitis, plus insufficient laboratory experience.
Other Information
Vaccination Recommended 

B
Section IV - Virus Properties
Physicochemical
 



(S)








1.23

(S)


(S)

Stability of Infectivity (effects)


1:5; 20 hr, 4dC

4.4 dex

7.6 dex




1:1000

2.0 dex

7.6 dex


Virion Morphology

Spherical

36 nm

nm

nm

Electron microscopy (2,3)

Envelope observed; diameter = 3-5 nm (3);


Morphogenesis






Hemagglutination

Yes

SMB ext. by sucrose-acetone**

Goose

6.0-6.6

6.2-6.4

4-37dC

21dC (room)

In density gradient at least two separable hemagglutinins, CF antigens and precipitins (3). * Pool of 14 females, 12 males, 182 nymphes and 93 larvae ** Also aqueous-prot. ext.; cell culture fluid; other methods, see Reference 4.

NT, HI, antibody absorption, immunodiffusion in ag

In density gradient at least two separable hemagglutinins, CF antigens and precipitins (3). * Pool of 14 females, 12 males, 182 nymphes and 93 larvae ** Also aqueous-prot. ext.; cell culture fluid; other methods, see Reference 4.
 
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