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Virus Name: Vesicular Stomatitis, New Jersey serotype

Abbreviation: VSNJV

Status
Possible Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Extensive laboratory experience and mild nature of aerosol laboratory infections justifies Level 2.

Other Information

Antigenic Group
Vesicular Stomatitis

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

CF tests (6):

	Hyperimmune Mouse Sera
Antigens	VS-New Jersey	VS-Indiana	Cocal	Piry	Chandipura


^a Titer of serum/titer of antigen; 0 = <4/4
VS-New Jersey	256/512 ^a	0	0	0	0
VS-Indiana	0	256/512	32/128	0	0
Cocal	0	32/512	256/512	0	0
Piry	0	0	0	128/32	8/4
Chandipura	0	0	0	0	128/64

Log Neutralization Tests (6)

	Hyperimmune Mouse Sera
Virus	Titer dex LD50	VS-New Jersey	VS-Indiana	Cocal	Piry	Chandipura


^b Log neutralization index in dex
VS-New Jersey	5.5	>=5.0 ^b	2.2	<1.5	<1.5	<1.5
VS-Indiana	7.1	1.9	>=6.2	4.2	<1.5	2.6
Cocal	7.7	2.7	4.2	>=7.0	1.7	1.8
Piry	7.9	2.5	2.3	2.6	5.7	3.4
Chandipura	7.3	<1.5	2.5	2.7	4.6	>=5.7

Plaque Reduction Neutralization Tests (7)

	Virus
Immune serum	VS-New Jersey	VS-Indiana	Cocal	Piry	Chandipura	Isfahan


^c Reciprocal of highest serum dilution producing >=95% plaque inhibition
VS-New Jersey	10240 ^c	<10	<10	<10	<10	<10
VS-Indiana	<10	327680	320	<10	<10	<10
Cocal	<10	160	5120	<10	<10	<10
Alagoas	<10	20	20	<10	<10	<10
Piry	<10	<10	<10	163840	80	<10
Chandipura	<10	<10	<10	<10	10240	<10
Isfahan	<10	<10	40	<10	<10	163840

For additional serologic test results, see Vesicular Stomatitis Alagoas registration card and Reference [6] .

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