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Trends in Prevalence of Diabetes

Trends in Prevalence of Diabetes

During 2001–March 2020, crude prevalence of diabetes increased from 9.0% to 14.1% in the U.S. adult population. Among adults with CKD, the crude and age-adjusted prevalence was on average threefold higher than among adults without CKD. During 2017–March 2020, the crude prevalence of diabetes was 37.4% among adults with CKD vs. 10.3% among adults without CKD. Among adults with CKD, diabetes prevalence (crude) was highest among those aged 60–69 years and males. The lowest prevalence of diabetes was seen among non-Hispanic White adults with CKD.

Data Source: NHANES

To view the burden of Diabetes by risk categories, select from the drop-down menu below. Risk categories include CKD, Age Category, Sex, and Race/Ethnicity.


Diabetes (%), Overall

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Data includes CKD stages 1–5. Estimates were standardized to the 2010 U.S. Census adult population.

Estimate for Age Category "18-39 years" was suppressed due to a large standard error stemming from a small sample size.

NHANES is a nationally representative, cross-sectional survey that is currently conducted every two years (since 1999) by CDC's National Center for Health Statistics among noninstitutionalized US civilian residents. The survey consists of a standardized in-home interview and a physical examination with blood and urine collected at a mobile examination center. Data were examined by combining two NHANES cycles to represent four-year periods from 2001 to 2016 and the 2017–March 2020 pre-pandemic cycle.

Note: Not all NHANES variables are collected for all years; therefore, some NHANES indicators may not utilize the full 20-year span.

FieldData
Description of Measure

Overall: Prevalence of diabetes among U.S. adults.

By strata: Prevalence of diabetes among U.S. adults with CKD.

Data Set

National Health and Nutrition Examination Survey (NHANES).

Population

Noninstitutionalized U.S. adults aged ≥ 18 years. Pregnant women excluded.

Years Included

2001–March 2020.

Numerator

Overall: U.S. adults aged ≥ 18 years with diabetes.

By strata: U.S. adults aged ≥ 18 years with CKD and diabetes.

Denominator

Overall: U.S. adults aged ≥ 18 years with data for CKD and diabetes.

By strata: U.S. adults aged ≥ 18 years with CKD (eGFR < 60 ml/min/1.73 m2 or albuminuria) and data for diabetes.

Definition of CKD

CKD is defined by an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m² or albuminuria (urine albumin to creatinine ratio [UACR] ≥ 30 mg/g). Estimates are based on single estimates of eGFR and UACR.

Estimated Glomerular Filtration Rate (eGFR)

Based on the CKD-EPI (2021) equation for calibrated creatinine: eGFR=142 x [min(serum creatinine in mg/dL) /κ, 1)]^α x [max(serum creatinine/κ, 1)]^-1.20 x 0.9938^age x (1.012 if female).
κ = 0.7 if female and 0.9 if male
α = -0.241 if female and -0.302 if male

Albuminuria

UACR was calculated as urine albumin divided by urine creatinine. Albuminuria is defined as UACR ≥ 30 mg/g. Urine albumin is measured in random urine collection by fluorescent immunoassay.

Serum Creatinine

Serum creatinine values used for eGFR calculation were standardized against isotope dilution mass spectrometry (IDMS).

Definition of Diabetes

Self-reported diabetes or HbA1c ≥ 6.5%.

Age Standardization

Estimates were standardized to the 2010 U.S. Census population for adults: 18–39 years: 37.1%, 40–59 years: 38.1%, 60–69 years: 12.8%, and 70+ years: 12.0%. 

Limitations of Indicator

Albuminuria and kidney function were assessed from one-time cross-sectional measurements, possibly overestimating CKD prevalence. 

Analytical Considerations

Appropriate NHANES survey weights were used for all analyses; if relative standard error is greater than 30%, the estimates are not shown. Serum creatinine measurements are assay corrected for NHANES years 2005 and 2006 and prior to be combined with later years.


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