4,4'-Methylenedianiline

CAS ID#: 101-77-9

Affected Organ Systems: Dermal (Skin), Hepatic (Liver)

Cancer Classification:  Please contact NTP, IARC, or EPA with questions on cancer and cancer classification.

Chemical Classification: Benzidines/Aromatic amines

Summary: 4,4'-Methylenedianiline is an industrial chemical that is not known to occur naturally. It is also commonly known as diaminodiphenylmethane or MDA. It occurs as a colorless to pale yellow solid and has a faint odor. 4,4'-Methylenedianiline is used mainly for making polyurethane foams, which have a variety of uses, such as insulating materials in mailing containers. It is also used for making coating materials, glues, Spandex® fiber, dyes, and rubber.

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Public Health Statement - Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile.

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Toxicological Profile - Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance.

Minimal Risk Levels (MRL) - The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure.

Page last reviewed: February 10, 2021
Content source: Agency for Toxic Substances and Disease Registry