1,3-Butadiene

CAS ID#: 106-99-0

Affected Organ Systems: Cancer, Developmental (effects while organs are developing), Gastrointestinal (Stomach and Intestines, part of the digestive system), Gastrointestinal (Stomach and Intestines, part of the digestive system), Hematological (Blood Forming), Neurological (Nervous System), Reproductive (Producing Children)

Cancer Classification:  Please contact NTP, IARC, or EPA with questions on cancer and cancer classification.

Chemical Classification: Volatile organic compounds

Summary: 1,3-Butadiene is a chemical made from the processing of petroleum. It is the 36th highest volume chemical produced in the United States. It is a colorless gas with a mild gasoline-like odor. About 75% of the manufactured 1,3-butadiene is used to make synthetic rubber. Synthetic rubber is widely used for tires on cars and trucks. 1,3-Butadiene is also used to make plastics including acrylics. Small amounts are found in gasoline.

Community Members
Community Members

ToxFAQs - Fact sheet that answers the most frequently asked questions about a contaminant and its health effects.

Public Health Statement - Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile.

Emergency Responders
Emergency Responders

Medical Management Guidelines (MMG) for Acute Chemical Exposure - Publication intended to aid emergency department physicians and other emergency healthcare professionals who manage acute exposures resulting from chemical incidents.

Toxicological and Health Professionals
Toxicological and Health Professionals

Toxicological Profile - Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance.

ToxGuidepdf icon[110 KB] - Quick reference guide providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects for a substance.

Priority List of Hazardous Substances - Prioritization of substances based on a combination of their frequency, toxicity, and potential for human exposure at National Priorities List (NPL) sites.

Minimal Risk Levels (MRL) - The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure.

Page last reviewed: February 10, 2021