ID#: 23625
Caption:
This image depicts a close left lateral view of the temporal region of a bed-ridden 2½-year-old male diagnosed with Langerhans cell histiocytosis (LCH), historically referred to as Letterer–Siwe disease and histiocytosis X. The image highlights crusted scalp lesions characteristic of LCH. LCH is characterized by clonal proliferation of pathologic Langerhans cells, a type of dendritic cell involved in immune function. The patient demonstrated features associated with the Hand–Schüller–Christian pattern, including exophthalmos and multiple lytic bony lesions, particularly involving the cranium; however, diabetes insipidus was not observed. A petechial cutaneous eruption was also present. See PHIL 23623 through 23628 for additional images documenting this patient’s condition.
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Content Provider(s): CDC/ Mr. Gust
Creation Date: 1967
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