ID#: 23628
Caption:
This image depicts a close view of the back of a bed-ridden 2½-year-old male diagnosed with Langerhans cell histiocytosis (LCH), historically referred to as Letterer–Siwe disease and histiocytosis X. LCH is characterized by clonal proliferation of pathologic Langerhans cells, a type of dendritic cell involved in immune function. The patient demonstrated features associated with the Hand–Schüller–Christian pattern, including exophthalmos and multiple lytic bony lesions, particularly involving the cranium; however, diabetes insipidus was not observed. This image shows a petechial cutaneous eruption with focal crusting. See PHIL 23623 through 23628 for additional images documenting this patient’s condition.
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Content Provider(s): CDC/ Mr. Gust
Creation Date: 1967
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