ID#: 23665
Caption:
This photograph depicts an anterior-inferior (AI) view of an 18-day-old female infant born with a rare X-linked dominant genetic disorder known as incontinentia pigmenti (IP). The disorder results from a mutation in the IKBKG (inhibitor of nuclear factor kappa B kinase subunit gamma) gene, which regulates production of IκB kinase (IkappaB kinase or IKK), a critical component of the cellular inflammatory response pathway. The infant exhibited a characteristic dry, scaly, erythematous rash involving the torso and extremities. See PHIL 23664 through 23671 for additional views documenting this infant’s condition at various stages of development.
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Content Provider(s): CDC/ Mr. Gust
Creation Date: 1967
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